进一步提高中西医结合防治肿瘤的临床研究水平

发布时间：2018-08-19 14:50

【摘要】：多年来对于中西医能否结合存在争议。近50—60年来,由于中医进入医院,和西医不同学科一样成为重要科室之一,一大批有作为的西医学习中医,因此得到互相认识、交流乃至结合的机会。改革开放以来的30年,政府提出中西医并举,结合的空间扩大,学术环境更自由了,思路也更具体了。世界医学重新重视自然和传统医学。在临床肿瘤学领域内,通过实践已经形成共识:在应用现代医学最大限度地杀灭或抑制肿瘤的同时通过中医调理扶正可以明显提高临床疗效,而且得到广大医师和患者接受和欢迎。而且在应用三氧化二砷静脉注射治疗急性早幼粒白血病(APL),并且发现它的作用机制是调控PML-RARa蛋白诱导凋亡;扶正中药能促进病人的细胞免疫功能已经成为临床医师的共识而且用于临床实践:人参成分之一Rg3作为新生血管抑制剂,和正在进行研究的冬凌草、康莱特、榄香烯等都有望取得进一步的成果。祖国医学在慢性病的调理上具有独特的作用。而调控正是21世纪医学的重要组成部分。靶向治疗本身就是在分子水平上的信息转导的调控,所以从理论上我国学者应当更容易理解"同病异治和异病同治"等原则,这和我们目前的个体化治疗是相通的。当前,我们应当抓住机遇通过中西医结合对世界医学作出我们民族的新贡献。而最大限度地应用现代医学方法开展高水平的临床试验,阐明祖国医学的很多观点,则是一个重要的桥梁。
[Abstract]:Over the years, there has been controversy over whether traditional Chinese and western medicine can be combined. In the past 50 to 60 years, because Chinese medicine entered the hospital and became one of the important departments as well as the different subjects of western medicine, a large number of western medicine who had done well studied Chinese medicine, so they got the opportunity to know each other, communicate and even combine with each other. In the 30 years since the reform and opening up, the government has proposed the development of both traditional Chinese and western medicine, the space for integration has expanded, the academic environment has become freer, and the ideas have become more specific. World medicine attaches renewed importance to natural and traditional medicine. In the field of clinical oncology, a consensus has been formed through practice: while using modern medicine to kill or suppress tumors to the maximum extent, it can obviously improve the clinical efficacy by regulating and rectifying the tumor through traditional Chinese medicine. And by the majority of doctors and patients accepted and welcomed. It was found that the mechanism of arsenic trioxide intravenously in the treatment of acute promyelocytic leukemia (APL),) was to regulate the apoptosis induced by PML-RARa protein. It has become a common understanding among clinicians that Fuzheng traditional Chinese medicine can promote the cellular immune function of patients: Rg3, one of the ingredients of ginseng, is used as a neovascularization inhibitor, and oridox, Kanglaite, which is being studied. Elemene and so on are expected to achieve further results. Chinese medicine plays a unique role in the management of chronic diseases. Regulation and control is an important part of medicine in the 21 st century. Target therapy itself is the regulation of information transduction at the molecular level. Therefore, in theory, Chinese scholars should understand more easily the principles of "same disease and different treatment", which is similar to our current individualized treatment. At present, we should seize the opportunity to make new contributions to world medicine through the integration of traditional Chinese and western medicine. It is an important bridge to use modern medical methods to carry out high level clinical trials and clarify many viewpoints of Chinese medicine.
【作者单位】：中国医学科学院北京协和医学院肿瘤医院;
【分类号】：R730.5

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