基于疾病的综合性实验课程建设

发布时间：2018-05-16 01:29

本文选题：基础医学 + 技术课程　；参考：《中国病理生理杂志》2013年10期

【摘要】：以疾病为切入点,选择若干影响人类健康的重大疾病为基本实验教学内容,整合基础医学相关学科理论和实验方法学,建设疾病相关的系统整合基础医学实验课程。该课程体系包括两部分,一是以疾病为中心的综合实验课程,二是研究与疾病相关的实验技术课程。前者将对临床医学专业全面开放作为必修,后者将面向长学制临床医学专业学生开放,作为选修。以疾病为中心的综合实验课程包括:心肌缺血/再灌注损伤的功能/形态变化与实验治疗、早老性痴呆的神经生物学改变与脑功能分析、胰岛素抵抗的形态学基础和功能变化、肿瘤生物学与治疗学、代偿性炎症反应综合症的病原生物学基础。疾病研究相关研究技术课程包括:形态学实验技术课程:组织切片技术;组织培养技术和机能学实验技术课程:生物信号处理技术和实验动物方法学技术;分子生物学技术课程。该部分内容作为选修课,可为培养长学制学生的科研能力提供有力条件。同时也扩大本课程体系的辐射作用,作为研究生、进修生的选修内容。该项课程改革的难点和重点在于实验教学内容的整合、衔接。实施这些课程拟贯穿整个基础医学教育阶段。从形态学早期认知疾病到机能学研究和实验治疗疾病,实现基础阶段对疾病过程的认识和分析。
[Abstract]:Taking disease as the starting point, selecting some major diseases that affect human health as the basic experimental teaching content, integrating the theory and experimental methodology of basic medicine, and constructing the disease related system integration of basic medical experiment course. The curriculum system consists of two parts, one is the disease-centered comprehensive experimental curriculum, the other is the research of disease-related experimental technology. The former will be open to clinical medicine as a compulsory course, while the latter will be open to long-term clinical medical students as an optional course. The comprehensive experimental courses centered on disease include: functional / morphological changes and experimental treatment of myocardial ischemia / reperfusion injury, neurobiological changes and brain function analysis of Alzheimer's disease, morphological basis and functional changes of insulin resistance. Tumor biology and therapeutics, the pathogenic biological basis of compensatory inflammatory response syndrome. The courses of disease research related technology include: morphological experimental technology course: tissue section technology; tissue culture technology and functional experimental technology course: biological signal processing technology and experimental animal methodology technology; Course in Molecular Biology Technology. As an elective course, this part can provide powerful conditions for cultivating the scientific research ability of long-term students. At the same time, it also expands the radiative function of the course system as an elective for graduate students. The difficulty and emphasis of the course reform lies in the integration and convergence of the experimental teaching contents. The implementation of these courses is intended to run through the whole stage of basic medical education. From morphological early cognitive diseases to functional research and experimental treatment of diseases, the basic stage of understanding and analysis of disease process.
【作者单位】：天津医科大学;
【分类号】：G642;R-4

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