糖有氧供能下不同周期游泳训练后大鼠肾脏功能恢复规律的研究

发布时间：2018-07-28 08:48

【摘要】：目的:探索在糖有氧供能条件下的间歇性游泳训练最佳训练周期及机制。方法:SD雄性大鼠随机分成空白对照组(C,n=6)、单周期/周训练组(小、中、大负荷循环1次,T_1,n=42)、双周期/周训练组(小、中、大负荷循环2次,T_2,n=42)、三周期/周训练组(小、大负荷循环3次,T_3,n=42)。大鼠经过一周不同训练周期游泳训练后,C组在安静状态下,T_1、T_2、T_3组在运动后7个时刻(T_0、T_(12)、T_(24)、T_(36)、T_(48)、T_(60)、T_(72))分别取血液、肾脏组织,测定CRE、SOD、MDA、Ca~(2+)-ATP酶等指标。结果:单周期训练结束后即刻大鼠血液中CRE含量显著升高(P0.05);肾脏组织中MDA含量即刻显著性升高;Ca~(2+)-ATPase含量在T_0和T_(12)表现为显著性降低(P0.05)。双周期训练结束后肾脏组织Ca~(2+)-ATPase含量各时相变化明显,在T_12、T_24和T_36分别为显著性降低和显著性回升;肾脏组织内SOD水平在即刻显著性降低,T_24和T_(36)显著性升高,T_(60)恢复至正常水平;即刻大鼠血液中CRE水平显著性升高,所以肾脏功能恢复的最佳时间为T_(48)至T_(60)。三周期训练后即刻大鼠血液中CRE含量显著性升高,T_(24)和T_(36)均表现显著性升高和回落,T_(72)时恢复正常;大鼠肾脏内的SOD含量水平在即刻显著性降低;与安静对照组相比,MDA在各时相有上升趋势,至T_72恢复至正常水平;肾脏组织内Ca~(2+)-AT_Pase水平在T_12、T_(24)和T_(48)均表现为显著性下降,所以肾脏功能恢复的最佳时间为T_(60)至T_(72)。结论:双周期训练后,肾脏功能恢复的最佳时段为48 h至60 h;三周期训练后肾脏功能恢复的最佳时间为60 h至72 h。
[Abstract]:Objective: to explore the best training cycle and mechanism of intermittent swimming training under the condition of glucose aerobic supply. Methods male Sprague-Dawley rats were randomly divided into three groups: blank control group (CX 6), single cycle / week training group (small, medium, heavy load cycle once), double cycle / week training group (small, medium and heavy load cycle 2 times), three-cycle / week training group (small, middle and heavy load cycle 2 times), and three cycle / week training group (small, middle, heavy load cycle 2 / week training group). Heavy load cycle 3 times T _ T _ 3 / T _ 3 / n ~ (42). After a week of swimming training in different training cycles, rats in group C collected blood, kidney tissues, and measured the indexes of CRESODU MDACa2 ~ (2) -ATPase at 7 postexercise points (T _ 0 / T _ (12) T _ (24) T _ (48) / T _ (60) T _ (72). Results: the content of CRE in blood and the content of MDA in renal tissue were significantly increased immediately after one-cycle training (P0.05) and the contents of Ca2-ATPase decreased significantly in T0 and T12 (P0.05). The contents of Ca ~ (2) -ATPase in renal tissue changed obviously at each time after two-cycle training, and the levels of SOD in renal tissue increased significantly from T24 to T36, and T60 to normal level at T _ (12) T _ (24) and T _ (36), respectively, and the contents of Ca ~ (2) -ATPase in renal tissue decreased significantly at the end of two-cycle training, and the contents of Ca ~ (2) -ATPase in renal tissue increased to normal level at T _ (12) T _ (24) and T _ (36) respectively. The level of CRE in blood of rats was significantly increased at once, so the best time for renal function recovery was from T48 to T60. The levels of CRE in blood of rats were significantly increased after three cycles of training. Both T24 and T36 showed significant increase and decrease of T72, and the level of SOD in the kidney of rats decreased significantly at the same time, and the contents of T24 and T36 in the blood of rats returned to normal immediately after three cycles of training, and the levels of T24 and T36 in the blood of the rats were significantly decreased at the same time. Compared with the quiet control group, MDA increased at all times, and the level of Ca ~ (2) -ATPase in renal tissue decreased significantly in T _ (12) T _ (24) and T _ (48), so the best time for the recovery of renal function was T60 to T72. Conclusion: after two-cycle training, the best time of renal function recovery is from 48 h to 60 h, and the best time after three cycles training is from 60 h to 72 h.
【作者单位】：成都大学;成都体育学院;
【分类号】：G804.2;G861.1

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