鸡RB1基因的生物信息学分析
发布时间:2018-08-26 13:49
【摘要】:以鸡的RB1基因为研究对象,运用生物信息学的方法对鸡等15种动物的RB1蛋白进行了多序列比对分析、分子进化分析及蛋白质结构分析,同时还比较了鸡、人及鼠的RB1基因结构、启动子结构以及3'端非编码区结构。结果表明:鸡和人RB1基因的进化关系较近,但是,从启动子结构、3'端非编码区结构来看,鸡RB1基因与人和小鼠的同源性很低。研究结果可以为下一步鸡RB1基因的功能研究提供参考依据。
[Abstract]:Using the RB1 gene of chicken as the research object, the RB1 protein of 15 kinds of animals were analyzed by bioinformatics. The molecular evolution analysis and protein structure analysis were carried out. The RB1 gene structure of chicken, human and mouse were also compared. Boot substructure and 3'- end non-coding region structure. The results showed that the evolutionary relationship between chicken RB1 gene and human RB1 gene was close, but chicken RB1 gene had low homology with human and mouse from the 3'noncoding region structure of promoter substructure. The results can provide reference for the further study on the function of chicken RB1 gene.
【作者单位】: 农业部鸡遗传育种重点实验室/黑龙江省普通高等学校动物遗传育种与繁殖重点实验室/东北农业大学动物科学技术学院;
【基金】:国家自然科学基金项目(31301960) 高等学校博士学科点专项科研基金新教师类资助课题(20132325120016) 黑龙江省普通本科高等学校青年创新人才培养计划项目(UNPYSCT-2015007) 黑龙江省教育厅面上项目(12541019) 黑龙江省博士后青年英才计划项目(QC2016023)
【分类号】:S831
本文编号:2205057
[Abstract]:Using the RB1 gene of chicken as the research object, the RB1 protein of 15 kinds of animals were analyzed by bioinformatics. The molecular evolution analysis and protein structure analysis were carried out. The RB1 gene structure of chicken, human and mouse were also compared. Boot substructure and 3'- end non-coding region structure. The results showed that the evolutionary relationship between chicken RB1 gene and human RB1 gene was close, but chicken RB1 gene had low homology with human and mouse from the 3'noncoding region structure of promoter substructure. The results can provide reference for the further study on the function of chicken RB1 gene.
【作者单位】: 农业部鸡遗传育种重点实验室/黑龙江省普通高等学校动物遗传育种与繁殖重点实验室/东北农业大学动物科学技术学院;
【基金】:国家自然科学基金项目(31301960) 高等学校博士学科点专项科研基金新教师类资助课题(20132325120016) 黑龙江省普通本科高等学校青年创新人才培养计划项目(UNPYSCT-2015007) 黑龙江省教育厅面上项目(12541019) 黑龙江省博士后青年英才计划项目(QC2016023)
【分类号】:S831
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1 陈曦;王宇祥;程博涵;李辉;;鸡RB1基因的组织表达特性研究[A];中国畜牧兽医学会家禽学分会第九次代表会议暨第十六次全国家禽学术讨论会论文集[C];2013年
,本文编号:2205057
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