生物医用PLA/OMMT复合纺织材料的制备及性能
发布时间：2021-12-29 01:22
随着近年来电纺纳米技术的发展,含有先进特性的纳米纤维的生产和开发认识到了潜在好处,如抗菌保护膜、创面绷带、医用防护服和其他医疗产品等生物医用纺织品的应用。现在,抗菌性能成为生物医用纺织品领域的重要性能。上述医疗产品的例子,如果上述产品具有抗菌性能,那么它们的应用是非常具有标志性的。抗菌生物医学纺织品的主要优点和目的是防止各种感染和快速愈合伤口并保持生物安全性。在生物医用纺织品的开发中,这些特殊用途的材料需要具有特殊的材料性能。包括具有良好的透气性、良好的吸收性能、最佳的热性能和机械性能以及良好的可纺性。材料的其他特性对医学应用十分重要,包括具有环保、生物安全性、生物降解性、吸收性好、光滑性好、不含杂质等特点。在纺织工业中,静电纺丝是一种适合于制造电纺丝聚合物纳米纤维、复合材料、聚合物共混物（用蒙脱土和有机改性蒙脱土等天然粘土）的技术,这种技术具有可改变的极性、渗透性和与最终用途相关的直径。静电纺丝参数对生产特定用途的聚合物纳米纤维起着关键作用。在这些关键参数中,最重要的是溶剂的选择。选择一种溶剂使聚合物溶解良好,使纳米纤维纺丝均匀,主要是基于对聚合物-溶剂机理的认识。这种溶剂的选择对控...
【文章来源】：江南大学江苏省 211工程院校 教育部直属院校
【文章页数】：122 页
【学位级别】：博士
【文章目录】：
Acknowledgement
Dedication
Abbreviations
Abstract
摘要
Chapter1 Literature review
1.1 Introduction of electrospinning
1.1.1 A historical background of electrospinning
1.1.2 Mechanism of electrospinning process
1.1.3 Influencing parameters for electrospinning process
1.1.4 Fabrication of nanofibers by electrospinning for biomedical textile applications
1.2 ATRP Technique
1.2.1 Introduction
1.2.2 Grafting monomer
1.3 Poly(lactic acid)polymer
1.3.1 Structure of PLA
1.3.2 Properties of PLA
1.4 Polymer/clay nanocomposites
1.4.1 Structure and composition of montmorillonite clay
1.4.2 Nanoclay Based Composites
1.4.3 Polylactic acid biomedical textile application
1.5 Antimicrobial photodynamic therapy
1.5.1 Introduction
1.5.2 History of photodynamic therapy
1.5.3 Antibacterial mechanism
1.5.4 Photosensitizers
1.5.5 Light sources used in photodynamic therapy
1.6 Problem Statement
1.7 Advantages of antibacterial photodynamic therapy(PDT)over antibiotics
1.8 Research objectives of the thesis
References
Chapter2 Preparation and characterization of antimicrobial electrospun PLA and OMMT hybrid nano-fabrics via dip-coating
2.1 Introduction
2.2 Experimental section
2.2.1 Materials
2.2.2 Production of PLA nanofiber
2.2.3 Synthesis of PLA/OMMT hybrid nanocomposites
2.2.4 Preparation of Methylene blue absorbed PLA)/OMMT hybrid nanocomposites
2.3 Characterization
2.4 Mechanical testing
2.5 Water absorption testing
2.6 Antibacterial photodynamic inactivation assay
2.7 Results and Discussion
2.7.1 Morphology of PLA nanofiber
2.7.2 Water absorption
2.7.3 Mechanical testing
2.7.4 Evaluation of antibacterial efficacy
2.8 Summary
References
Chapter3 Characterization of electrospun membranes fabricated via solution of PLA/organo modified MMT
3.1 Introduction
3.2 Experimental section
3.2.1 Materials
3.2.2 Instrumentation
3.2.3 Preparation of PLA/OMMT blend solutions
3.2.4 Electrospinning of PLA/MMT nanofibers membranes
3.3 Result and discussion
3.3.1 Effect of PLA solution concentration
3.3.2 Effect of OMMT contents
3.3.3 Fourier transform infrared(FT-IR)analysis
3.3.4 Air permeability
3.4 Summary
References
Chapter4 Antimicrobial activity of2 dimethylaminoethyl methacrylate graft poly lactic acid nanofiber Membrane via Graft copolymerization
4.1 Introduction
4.2 Experimental section
4.2.1 Materials
4.2.2 Instrumentation:
4.2.3 Fabrication of electrospun PLA solutions
4.2.4 ATRP copolymerization technique
4.2.5 Quaternization modification of bacterial PLA copolymer
4.2.6 Characterization of nanofiber membrane
4.2.7 Antibacterial studies
4.3 Results and discussion
4.4 Summary
References
Chapter5 Preparation of photodynamic PLA composite nanofibers doped with MMT:a facile method for increasing antimicrobial efficiency
5.1 Introduction
5.2 Experimetal section
5.2.1 Materials
5.2.2 Electrospinning of PLA/OMMT nanofibers membranes
5.2.3 Characterization of electrospun PLA/OMMT nanofibers membranes
5.2.4 Mechanical performance
5.2.5 Contact angle
5.2.6 Thermal properties
5.2.7 Preparation of methylene blue absorbed PLA)/OMMT composite nanofibers membranes
5.2.8 Antibacterial photodynamic inactivation assay
5.3 Results and discussion
5.3.1 Structural morphology
5.3.2 Fourier transform infrared(FTIR)spectroscopy
5.3.3 Surface composition analysis
5.3.4 Water absorbency
5.3.5 Mechanical testing
5.3.6 Thermal properties
5.3.7 Evaluation of antibacterial efficacy
5.4 Summary
References
Chapter6 Conclusion and recommendations
List of Publications
本文编号：3555115
【文章来源】：江南大学江苏省 211工程院校 教育部直属院校
【文章页数】：122 页
【学位级别】：博士
【文章目录】：
Acknowledgement
Dedication
Abbreviations
Abstract
摘要
Chapter1 Literature review
1.1 Introduction of electrospinning
1.1.1 A historical background of electrospinning
1.1.2 Mechanism of electrospinning process
1.1.3 Influencing parameters for electrospinning process
1.1.4 Fabrication of nanofibers by electrospinning for biomedical textile applications
1.2 ATRP Technique
1.2.1 Introduction
1.2.2 Grafting monomer
1.3 Poly(lactic acid)polymer
1.3.1 Structure of PLA
1.3.2 Properties of PLA
1.4 Polymer/clay nanocomposites
1.4.1 Structure and composition of montmorillonite clay
1.4.2 Nanoclay Based Composites
1.4.3 Polylactic acid biomedical textile application
1.5 Antimicrobial photodynamic therapy
1.5.1 Introduction
1.5.2 History of photodynamic therapy
1.5.3 Antibacterial mechanism
1.5.4 Photosensitizers
1.5.5 Light sources used in photodynamic therapy
1.6 Problem Statement
1.7 Advantages of antibacterial photodynamic therapy(PDT)over antibiotics
1.8 Research objectives of the thesis
References
Chapter2 Preparation and characterization of antimicrobial electrospun PLA and OMMT hybrid nano-fabrics via dip-coating
2.1 Introduction
2.2 Experimental section
2.2.1 Materials
2.2.2 Production of PLA nanofiber
2.2.3 Synthesis of PLA/OMMT hybrid nanocomposites
2.2.4 Preparation of Methylene blue absorbed PLA)/OMMT hybrid nanocomposites
2.3 Characterization
2.4 Mechanical testing
2.5 Water absorption testing
2.6 Antibacterial photodynamic inactivation assay
2.7 Results and Discussion
2.7.1 Morphology of PLA nanofiber
2.7.2 Water absorption
2.7.3 Mechanical testing
2.7.4 Evaluation of antibacterial efficacy
2.8 Summary
References
Chapter3 Characterization of electrospun membranes fabricated via solution of PLA/organo modified MMT
3.1 Introduction
3.2 Experimental section
3.2.1 Materials
3.2.2 Instrumentation
3.2.3 Preparation of PLA/OMMT blend solutions
3.2.4 Electrospinning of PLA/MMT nanofibers membranes
3.3 Result and discussion
3.3.1 Effect of PLA solution concentration
3.3.2 Effect of OMMT contents
3.3.3 Fourier transform infrared(FT-IR)analysis
3.3.4 Air permeability
3.4 Summary
References
Chapter4 Antimicrobial activity of2 dimethylaminoethyl methacrylate graft poly lactic acid nanofiber Membrane via Graft copolymerization
4.1 Introduction
4.2 Experimental section
4.2.1 Materials
4.2.2 Instrumentation:
4.2.3 Fabrication of electrospun PLA solutions
4.2.4 ATRP copolymerization technique
4.2.5 Quaternization modification of bacterial PLA copolymer
4.2.6 Characterization of nanofiber membrane
4.2.7 Antibacterial studies
4.3 Results and discussion
4.4 Summary
References
Chapter5 Preparation of photodynamic PLA composite nanofibers doped with MMT:a facile method for increasing antimicrobial efficiency
5.1 Introduction
5.2 Experimetal section
5.2.1 Materials
5.2.2 Electrospinning of PLA/OMMT nanofibers membranes
5.2.3 Characterization of electrospun PLA/OMMT nanofibers membranes
5.2.4 Mechanical performance
5.2.5 Contact angle
5.2.6 Thermal properties
5.2.7 Preparation of methylene blue absorbed PLA)/OMMT composite nanofibers membranes
5.2.8 Antibacterial photodynamic inactivation assay
5.3 Results and discussion
5.3.1 Structural morphology
5.3.2 Fourier transform infrared(FTIR)spectroscopy
5.3.3 Surface composition analysis
5.3.4 Water absorbency
5.3.5 Mechanical testing
5.3.6 Thermal properties
5.3.7 Evaluation of antibacterial efficacy
5.4 Summary
References
Chapter6 Conclusion and recommendations
List of Publications
本文编号：3555115
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