人死后玻璃体液化学成分含量改变与死亡时间关系的研究

发布时间：2018-07-09 14:11

本文选题：法医学 + 人玻璃体液　；参考：《四川大学》2005年博士论文

【摘要】：死亡时间的推断(the estimation of the time since death)是法医学的核心问题之一,推断死亡时间亦是法医学尸体解剖要求解决的重要问题之一。法医学者准确地推断出死亡时间,可以重建案件,对案件的侦破和审理有重要的价值。当前推断死亡时间的方法主要包括:根据尸冷推断死亡时间;根据超生反应(supravital reaction)推断死亡时间;根据死后死者胃肠内容物的消化情况推断死亡时间;根据DNA降解程度推断死亡时间;根据酶组织化学和组织学变化推断死亡时间;利用昆虫学知识推断死亡时间。由于上述方法以半定量为主,主观性较强,因而使其应用受到限制。而根据死后尸体体液中化学成分的变化推断死亡时间以定量为主,客观性强,应用方便。人体体液主要包括血液、脑脊液、玻璃体液等。由于玻璃体在眼球中的特殊位置,尸体腐败和外界污染以及环境因素(温度除外)对其影响甚小,因此,玻璃体液的测定最为可靠,一直是法医病理学家研究的热点之一。目的: 1.测定健康人死后极短时间内眼球玻璃体液化学成分的含量,获得正常人玻璃体液的临床参考值。 2.用测定人死后玻璃体液化学成分含量来推断死亡时间,对多种化学指标进行分析,建立各自的回归方程,综合分析,提高可信度,使玻璃体液化学成分的测定能更广泛地应用于法医实践。方法: 1.用日本产OLYMPUS AU5400自动生化仪测定玻璃体液中葡萄糖等化
[Abstract]:Estimating the time of death (the estimation of the time since death) is one of the core problems in forensic medicine, and inferring the time of death is also one of the most important problems to be solved by forensic autopsy. Forensic scholars infer the time of death accurately, can reconstruct the case, and have important value for the detection and trial of the case. The current methods of estimating the time of death include: inferring the time of death according to autopsy, estimating the time of death by (supravital reaction), inferring the time of death according to the digestion of gastrointestinal contents of dead person; The time of death was inferred according to the degree of DNA degradation, the time of death according to the changes of histochemistry and histology of enzyme, and the time of death was inferred by using entomological knowledge. Because the above method is semi-quantitative and subjective, its application is limited. According to the changes of chemical composition in postmortem body fluid, the time of death is mainly quantitative, objective and convenient to use. Body fluids mainly include blood, cerebrospinal fluid, glass fluid and so on. Because of the special position of vitreous body in the eyeball, corpses, external pollution and environmental factors (except temperature) have little influence on it. Therefore, the determination of vitreous body fluid is the most reliable and has been one of the hot topics of forensic pathologists. Objective: 1. The contents of chemical constituents of vitreous fluid of eyeball were determined in a very short time after death in healthy people, and the clinical reference value of normal human vitreous fluid was obtained. 2. 2. The death time was inferred by measuring the chemical composition of vitreous body fluid after death, and a variety of chemical indexes were analyzed, their regression equations were established, and the reliability was improved by comprehensive analysis. So that the determination of chemical composition of vitreous body fluid can be more widely used in forensic practice. Methods: 1. Determination of glucose and glucose in vitreous body fluid by Auto-Biochemistry instrument of OLYMPUS AU5400 made in Japan
【学位授予单位】：四川大学
【学位级别】：博士
【学位授予年份】：2005
【分类号】：D919

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