儿童青少年抑郁症的病理研究进展

发布时间：2018-04-03 20:45

本文选题：儿童青少年抑郁症　切入点：影像学研究　出处：《中国特殊教育》2017年10期

【摘要】：医学、生物学的多个分支学科在儿童青少年抑郁症的研究上取得一些积极成果。认知行为研究发现,患者的静息态脑功能异常、神经递质功率失调、脑电α波左右不对称;核磁共振等影像学发现,患者的前额叶、海马等脑结构和代谢存在异常;神经电生理研究发现,患者的快波睡眠波、慢波睡眠波等脑电活动与正常人有差异;在神经递质的研究上,患者的去甲肾上腺素、多巴胺、5-羟色胺、γ-氨基丁酸以及神经肽等存在异常;遗传学研究表明,该症的发生有遗传因素的影响;免疫学研究认为白介素-1β、白介素-6、肿瘤坏死因子-α以及炎性细胞因子等的异常是抑郁症发生的重要因素。这些研究成果对抑郁症儿童青少年的诊断治疗、教育训练、抚养和安置有一定参考价值。
[Abstract]:Several branches of medicine and biology have achieved some positive results in the study of depression in children and adolescents.Cognitive behavior study found that patients with resting brain dysfunction, neurotransmitter power imbalance, EEG 伪 wave left and right asymmetry, MRI and other imaging findings, the patient's prefrontal lobe, hippocampus and other brain structure and metabolism abnormalities;Neuroelectrophysiological studies have found that the EEG activity of patients with rapid sleep waves and slow wave sleep waves is different from that of normal people, and that in the study of neurotransmitters, the patients have norepinephrine,There are abnormalities in dopamine 5-hydroxytryptamine gamma-aminobutyric acid and neuropeptide.Immunological studies suggest that the abnormalities of interleukin-1 尾, interleukin-6, tumor necrosis factor- 伪 and inflammatory cytokines are important factors in the occurrence of depression.These results have some reference value for diagnosis and treatment, education, training, upbringing and placement of children and adolescents with depression.
【作者单位】：华东师范大学特殊教育学系;
【分类号】：B844

【相似文献】