个体内感受在焦虑中的作用及其神经机制
发布时间:2022-10-06 16:57
内感受(interoception)是指个体对来自身体内部的生理信号的知觉,包括饿,饱,渴,胀,冷,热,肌肉松紧,心跳,呼吸等(Cameron,2001;Sherrington,1906;Craig,2002;Khalsa etal.,2017)。虽然内感受的定义一 直受到争议,但是越来越多的学者认为内感受并不是一个单一的过程,而是包括几个不同维度的复杂过程,如内感受注意(interoceptive attention,注意来自身体的感觉)、内感受准确性(interoceptive accuracy,使用客观的行为测试测得的对身体知觉的准确度),内感受感性(interoceptive sensibility,使用自我报告的方式测得的身体知觉的行为风格)等(Ceunen,Vlaeyen,&Van Diest,2013;Garfinkel,Seth,Barrett,Suzuki,&Critchley,2015;Khalsaetal.,2017)。内感受在维持身体内稳态,症状知觉,情绪体验,自我调控,决策过程和自我意识中都起关键作用(Khalsa et al.,2017)。而且,在多种精神疾...
【文章页数】:169 页
【学位级别】:博士
【文章目录】:
摘要
ABSTRACT
CHAPTER 1 GENERAL INTRODUCTION
1.1 INTEROCEPTION
1.2 ANXIETY
1.3 INTEROCEPTION AND ANXIETY
CHAPTER 2 FORMULATION OF HYPOTHESES
2.1 RESEARCH GAPS
2.2 RESEARCH PLANS AND HYPOTHESES
2.3 IMPORTANCE AND INNOVATIONS
CHAPTER 3 STUDY 1: THE BEHAVIORAL RELATIONS BETWEEN INTEROCEPTION AND ANXIETY
3.1 INTRODUCTION
3.2 STUDY 1=A: THE CORRELATIONS BETWEEN INTEROCEPTION AND ANXIETY
3.3 STUDY 1=B: THE MODERATING EFFECT OF EMOTION REGULATION ON THE RELATIONSHIPS BETWEEN INTEROCEPTION AND ANXIETY
3.4 DISCUSSION
3.5 CONCLUSION
CHAPTER 4 STUDY 2: NEURAL MECHANISMS UNDERLYING THE RELATIONSHIPS BETWEEN INTEROCEPTION AND ANXIETY: FMRI INVESTIGATIONS
4.1 INTRODUCTION
4.2 STUDY 2-a: UNITY AND DIVERSITY OF THE NEURAL SUBSTRATES OF INTEROCEPTION AND ANXIETY
4.3 STUDY 2-b: INTEROCEPTION=RELATED INSULAR ACTIVITY AND ANXIETY
4.4 DISCUSSION
4.5 CONCLUSION
CHAPTER 5 STUDY 3: THE ERROR@RELATED NEGATIVITY FOR ERROR PROCESSING IN INTEROCEPTION AND ITS RELATES TO ANXIETY
5.1 INTRODUCTION
5.2 METHODS
5.3 RESULTS
5.4 DISCUSSION
5.5 CONCLUSIONS
CHAPTER 6 STUDY 4: THE IMPACT OF UNPREDICTABILITY OF INTEROCEPTIVE THREAT ON ANXIETY AND INTEROCEPTION
6.1 INTRODUCTION
6.2 METHODS
6.3 RESULTS
6.4 DISCUSSION
6.5 CONCLUSION
CHAPTER 7 GENERAL DISCUSSION
7.1 SUMMARY OF RESULTS
7.2 BEHAVIORAL FACTORS
7.3 NEURAL MECHANISMS
7.4 CLINICAL IMPLICATIONS
7.5 LIMITATIONS AND FUTURE RESEARCH
7.6 GENERAL CONCLUSION
REFERENCES
ACKNOWLEDGEMENTS
PUBLICATIONS
【参考文献】:
期刊论文
[1]内感受对成瘾行为的诱导及其岛叶的调控机制[J]. 李春禄,朱宁,李勇辉,孟肖路,高军,隋南. 生物化学与生物物理进展. 2013(01)
[2]焦虑障碍患者心跳知觉的研究进展[J]. 李惠,李春波,王继军,肖泽萍. 上海交通大学学报(医学版). 2012(07)
本文编号:3687024
【文章页数】:169 页
【学位级别】:博士
【文章目录】:
摘要
ABSTRACT
CHAPTER 1 GENERAL INTRODUCTION
1.1 INTEROCEPTION
1.2 ANXIETY
1.3 INTEROCEPTION AND ANXIETY
CHAPTER 2 FORMULATION OF HYPOTHESES
2.1 RESEARCH GAPS
2.2 RESEARCH PLANS AND HYPOTHESES
2.3 IMPORTANCE AND INNOVATIONS
CHAPTER 3 STUDY 1: THE BEHAVIORAL RELATIONS BETWEEN INTEROCEPTION AND ANXIETY
3.1 INTRODUCTION
3.2 STUDY 1=A: THE CORRELATIONS BETWEEN INTEROCEPTION AND ANXIETY
3.3 STUDY 1=B: THE MODERATING EFFECT OF EMOTION REGULATION ON THE RELATIONSHIPS BETWEEN INTEROCEPTION AND ANXIETY
3.4 DISCUSSION
3.5 CONCLUSION
CHAPTER 4 STUDY 2: NEURAL MECHANISMS UNDERLYING THE RELATIONSHIPS BETWEEN INTEROCEPTION AND ANXIETY: FMRI INVESTIGATIONS
4.1 INTRODUCTION
4.2 STUDY 2-a: UNITY AND DIVERSITY OF THE NEURAL SUBSTRATES OF INTEROCEPTION AND ANXIETY
4.3 STUDY 2-b: INTEROCEPTION=RELATED INSULAR ACTIVITY AND ANXIETY
4.4 DISCUSSION
4.5 CONCLUSION
CHAPTER 5 STUDY 3: THE ERROR@RELATED NEGATIVITY FOR ERROR PROCESSING IN INTEROCEPTION AND ITS RELATES TO ANXIETY
5.1 INTRODUCTION
5.2 METHODS
5.3 RESULTS
5.4 DISCUSSION
5.5 CONCLUSIONS
CHAPTER 6 STUDY 4: THE IMPACT OF UNPREDICTABILITY OF INTEROCEPTIVE THREAT ON ANXIETY AND INTEROCEPTION
6.1 INTRODUCTION
6.2 METHODS
6.3 RESULTS
6.4 DISCUSSION
6.5 CONCLUSION
CHAPTER 7 GENERAL DISCUSSION
7.1 SUMMARY OF RESULTS
7.2 BEHAVIORAL FACTORS
7.3 NEURAL MECHANISMS
7.4 CLINICAL IMPLICATIONS
7.5 LIMITATIONS AND FUTURE RESEARCH
7.6 GENERAL CONCLUSION
REFERENCES
ACKNOWLEDGEMENTS
PUBLICATIONS
【参考文献】:
期刊论文
[1]内感受对成瘾行为的诱导及其岛叶的调控机制[J]. 李春禄,朱宁,李勇辉,孟肖路,高军,隋南. 生物化学与生物物理进展. 2013(01)
[2]焦虑障碍患者心跳知觉的研究进展[J]. 李惠,李春波,王继军,肖泽萍. 上海交通大学学报(医学版). 2012(07)
本文编号:3687024
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