加味痛泻要方治疗肝郁脾虚型D-IBS的临床研究

发布时间：2018-04-10 02:06

  本文选题：肝郁脾虚　切入点：加味痛泻要方　出处：《广州中医药大学》2017年硕士论文

【摘要】：目的:探讨加味痛泻要方治疗肝郁脾虚型D-IBS的临床疗效,为中医药治疗肝郁脾虚型D-IBS提供依据、思路及用药参考。方法:选择符合肝郁脾虚型D-IBS诊断标准的病例60例,按就诊先后顺序排序随机分为2组,每组30例,分别设为中药治疗组和西药治疗组,治疗组治疗前、后均根据症状分级量化标准进行评分并同时观察不良反应。结果:1.中药治疗组治疗肝郁脾虚型D-IBS患者,总有效率达96.7%;西药治疗组治疗肝郁脾虚型D-IBS患者,总有效率达70.0%;两组比较差异有统计学意义(P0.05)。2.治疗组治疗后各主要症状积分及症状总积分均比治疗前显著降低,差异有统计学意义(P0.05)。3.中药治疗组治疗后各主要症状积分及症状总积分均低于西药治疗组,差异有统计学意义(P0.05)。结论:加味痛泻要方对肝郁脾虚型D-IBS患者有良好疗效,治疗过程中未发现明显不良反应,其临床疗效优于匹维溴铵。
[Abstract]:Objective: to explore the clinical effect of Jiawei Tongxieshuo recipe in the treatment of D-IBS with liver stagnation and spleen deficiency, and to provide the basis, train of thought and medication reference for traditional Chinese medicine in the treatment of D-IBS with liver stagnation and spleen deficiency.Methods: sixty cases of D-IBS with liver stagnation and spleen deficiency were randomly divided into two groups, 30 cases in each group, which were divided into two groups: traditional Chinese medicine treatment group and western medicine treatment group, before treatment, the treatment group was divided into two groups.All the patients were graded according to the criteria of symptom grading and adverse reactions were observed at the same time.The result is 1: 1.The total effective rate was 96.7in the treatment group of D-IBS with liver stagnation and spleen deficiency and 70.010 in the western medicine treatment group. The difference between the two groups was statistically significant (P 0.05). 2.After treatment, the scores of major symptoms and the total scores of symptoms in the treatment group were significantly lower than those before treatment, and the difference was statistically significant (P 0.05).The scores of major symptoms and symptoms in the treatment group were lower than those in the western medicine group, and the difference was statistically significant (P 0.05).Conclusion: Jiawei Tongxieyao recipe has good curative effect on D-IBS patients with liver stagnation and spleen deficiency, and no obvious adverse reaction was found in the course of treatment, and its clinical curative effect is superior to that of piveronium bromide.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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