NLR、PLR和CRP在小儿肺炎中的临床意义
发布时间：2019-01-10 11:48
【摘要】：目的:探讨中性粒细胞与淋巴细胞比值(Neutrophils and lymphocytes ratio,NLR)、血小板与淋巴细胞比值(Platelets and lymphocytes ratio,PLR)及 C-反应蛋白(C-reactiveprotein,CRP)与小儿肺炎诊断及严重程度的关系。方法:选择妇幼保健院中健康儿童50例作为对照组;选择2015年1月1日至2015年12月31日在本院儿科住院的100例肺炎患儿,分为重症肺炎组50例,轻症肺炎组50例。检测健康儿童、肺炎患儿入院时的血常规和CRP值,计算中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞的比值(pLR),分析NLR、PLR和CRP与肺炎的诊断及严重程度的关系。结果:1.对照组儿童NLR平均值为0.50±0.02,肺炎组患儿NLR平均值为2.73±0.22,两组NLR平均值比较有统计学意义(P0.05),轻症肺炎NLR平均值为1.5±0.2,重症肺炎NLR平均值为3.96±0.40,两组比较有统计学意义(P0.05)。2.对照组儿童PLR平均值为52.0±3.5,肺炎组患儿为166.0±11.5,两组比较有统计学意义(P0.05),轻症肺炎PLR平均值为151±13,重症肺炎PLR平均值为182±13,两组比较有统计学意义(P0.05)。3.对照组儿童CRP平均值为3.5±0.3mg/L,肺炎组为22.81±2.11mg/L,两组比较有统计学意义(P0.05),轻症肺炎患儿CRP平均值为15.3±1.4mg/L,重症肺炎为30.32±2.20mg/L,两组比较有统计学意义(P0.05)。结论:NLR、PLR和CRP可作为诊断儿童肺炎的参考指标,三种指标可鉴别患儿肺炎严重程度。
[Abstract]:Objective: to investigate the relationship between the ratio of neutrophil to lymphocyte (Neutrophils and lymphocytes ratio,NLR), platelet-lymphocyte ratio (Platelets and lymphocytes ratio,PLR) and C-reactive protein (C-reactive protein) in the diagnosis and severity of pneumonia in children. Methods: 50 healthy children in MCH hospital were selected as control group, and 100 children with pneumonia were divided into severe pneumonia group (n = 50) and mild pneumonia group (n = 50) from January 1, 2015 to December 31, 2015. The blood routine and CRP were measured at admission in healthy children and children with pneumonia. The ratio of neutrophil to lymphocyte (NLR), the ratio of platelet to lymphocyte (pLR),) were calculated to analyze the relationship between NLR,PLR, CRP and the diagnosis and severity of pneumonia. Results: 1. The average value of NLR was 0.50 卤0.02 in control group and 2.73 卤0.22 in pneumonia group. There was significant difference in NLR between the two groups (P0.05). The mean value of NLR in mild pneumonia was 1.5 卤0.2. The average NLR of severe pneumonia was 3.96 卤0.40, which was statistically significant (P0.05). The average value of PLR in control group was 52.0 卤3.5, and that in pneumonia group was 166.0 卤11.5. There was significant difference between the two groups (P0.05). The mean PLR of mild pneumonia was 151 卤13, and that of severe pneumonia was 182 卤13. There was statistical significance between the two groups (P0.05). The average CRP of control group was 3.5 卤0.3 mg / L, and that of pneumonia group was 22.81 卤2.11 mg / L (P0.05). The mean CRP of mild pneumonia group was 15.3 卤1.4 mg / L, respectively. Severe pneumonia was 30.32 卤2.20 mg / L, there was significant difference between the two groups (P0.05). Conclusion: NLR,PLR and CRP can be used as reference indexes in the diagnosis of pneumonia in children.
【学位授予单位】：延边大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.6
，
本文编号：2406268
[Abstract]:Objective: to investigate the relationship between the ratio of neutrophil to lymphocyte (Neutrophils and lymphocytes ratio,NLR), platelet-lymphocyte ratio (Platelets and lymphocytes ratio,PLR) and C-reactive protein (C-reactive protein) in the diagnosis and severity of pneumonia in children. Methods: 50 healthy children in MCH hospital were selected as control group, and 100 children with pneumonia were divided into severe pneumonia group (n = 50) and mild pneumonia group (n = 50) from January 1, 2015 to December 31, 2015. The blood routine and CRP were measured at admission in healthy children and children with pneumonia. The ratio of neutrophil to lymphocyte (NLR), the ratio of platelet to lymphocyte (pLR),) were calculated to analyze the relationship between NLR,PLR, CRP and the diagnosis and severity of pneumonia. Results: 1. The average value of NLR was 0.50 卤0.02 in control group and 2.73 卤0.22 in pneumonia group. There was significant difference in NLR between the two groups (P0.05). The mean value of NLR in mild pneumonia was 1.5 卤0.2. The average NLR of severe pneumonia was 3.96 卤0.40, which was statistically significant (P0.05). The average value of PLR in control group was 52.0 卤3.5, and that in pneumonia group was 166.0 卤11.5. There was significant difference between the two groups (P0.05). The mean PLR of mild pneumonia was 151 卤13, and that of severe pneumonia was 182 卤13. There was statistical significance between the two groups (P0.05). The average CRP of control group was 3.5 卤0.3 mg / L, and that of pneumonia group was 22.81 卤2.11 mg / L (P0.05). The mean CRP of mild pneumonia group was 15.3 卤1.4 mg / L, respectively. Severe pneumonia was 30.32 卤2.20 mg / L, there was significant difference between the two groups (P0.05). Conclusion: NLR,PLR and CRP can be used as reference indexes in the diagnosis of pneumonia in children.
【学位授予单位】：延边大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.6
，
本文编号：2406268
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