质子治疗束配系统电离室电子学研究

发布时间：2018-02-06 03:41

本文关键词： 核电子学自由空气平板电离室剂量电离室位置电离室质子治疗　出处：《中国科学院研究生院(上海应用物理研究所)》2017年博士论文　论文类型：学位论文

【摘要】：质子治疗束配系统的主要功能是将加速器引出的束流转换为治疗束流,并将治疗束流准确照射在目标组织上,如何精确测量质子束流的剂量、位置是整个束配系统的关键。上海质子治疗装置采用自由空气平板电离室作为剂量电离室,自由空气条带平板电离室作为位置电离室。剂量电离室电子学、位置电离室电子学是上海质子治疗装置点扫描束配系统的关键设备,其性能影响治疗剂量和剂量分布的精确性。本文根据束配系统指标、加速器慢引出束流参数和剂量电离室、位置电离室参数,提出了剂量电离室电子学和位置电离室电子学指标;确定了剂量电离室电子学和位置电离室电子学的技术方案,设计了两种不同的电子学。剂量电离室电子学采用I/V(Current to Voltage)+ADC(Analog to Digital Converter)方案,位置电离室电子学则采用传统电容积分法,两种电子学均实现前端数字化,安装在电离室内部。最终搭建测试平台,完成了实验室测试。从实验结果来看,剂量电离室电子学积分非线性±0.04n A,电子学分辨率±0.6n A(2 sigma);位置电离室电子学分辨率0.1nA(rms)。结果表明其性能已达到预期指标。本文对深入了解质子或重离子治疗束配系统电离室电子学的设计具有实际参考价值。作者研制了适用于质子治疗装置束配系统电离室的电子学,确保了束配系统照射剂量及剂量分布的准确性。
[Abstract]:The main function of the proton therapy beam matching system is to convert the beam produced by the accelerator into the treatment beam, and to accurately illuminate the therapeutic beam on the target tissue, how to accurately measure the dose of the proton beam. The position is the key of the whole bundle matching system. The Shanghai proton therapy device uses the free air flat ionization chamber as the dose ionization chamber and the free air strip plate ionization chamber as the position ionization chamber. The dose ionization chamber is electronic. Position ionization chamber electronics is the key equipment of the spot scanning beam matching system of Shanghai proton therapy facility. Its performance affects the accuracy of dose and dose distribution. The beam parameters, dose ionization chamber and position ionization chamber parameters are slowly extracted from the accelerator. The electronic and electronic indexes of the dose ionization chamber are presented. The technical scheme of dose ionization chamber electronics and position ionization chamber electronics is determined. Two different kinds of electronics have been designed. Dose ionization chamber electronics uses I / V current to VoltageADC. Analog to Digital conversion scheme. The position ionization chamber electronics adopts the traditional capacitance integration method. Both kinds of electronics realize the front end digitization and install in the ionization chamber. Finally, the test platform is built and the laboratory test is completed. The electron integral of dose ionization chamber is nonlinear 卤0.04nA, and the electronic resolution is 卤0.6nA ~ (2) sigma. Position ionization chamber electronic resolution 0.1nAn RMS). The results show that its performance has reached the expected target. This paper has practical reference value for further understanding the electronic design of ionization chamber of proton or heavy ion therapy bundle matching system. Electronics in the ionization chamber. The accuracy of irradiation dose and dose distribution of bundle matching system is ensured.
【学位授予单位】：中国科学院研究生院(上海应用物理研究所)
【学位级别】：博士
【学位授予年份】：2017
【分类号】：R815

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