梅尼埃病患者内耳内淋巴间隙显像与临床特征的相关性研究

发布时间：2018-06-08 13:57

  本文选题：内淋巴显像 + 梅尼埃病　； 参考：《临床耳鼻咽喉头颈外科杂志》2017年08期

【摘要】：目的:探讨梅尼埃病患者组内耳内淋巴间隙显像与临床特征(上次眩晕发作结束距MRI扫描时间)的相关性。方法:梅尼埃病患者26例29侧患耳,根据患者的临床特征,将受试者分为A组和B组。其中,A组为MRI扫描时无眩晕发作且距上次眩晕发作结束14d的患者,共12例14侧耳;B组为扫描时处于眩晕发作期或距上次眩晕发作结束≤14d的患者,共14例15侧耳。在鼻内镜引导下,将稀释的钆喷酸葡胺注射液通过咽鼓管注入患耳中耳腔,给药1d后行3D-FLAIR MRI扫描,得到内耳内淋巴间隙的显影,并对内耳内淋巴间隙、总淋巴间隙进行测量和计算,得到内耳内淋巴间隙与总淋巴间隙的比值。结果:26例梅尼埃病患者共29侧患耳经咽鼓管中耳腔给药成功。其中26侧患耳前庭及耳蜗内淋巴间隙均得到显影;B组3例患者(例6、例12、例14)的扫描图像中,其耳蜗和半规管均得到增强显影,而前庭未显影。A组前庭均值为0.37±0.06,耳蜗均值为0.15±0.04;B组前庭均值为0.52±0.26,耳蜗均值为0.18±0.06。ANOVA结果显示,两组前庭均值比较差异有统计学意义(P0.05),耳蜗均值比较差异无统计学意义(P0.05)。其中A组耳蜗内淋巴积水阳性率为7.1%,前庭内淋巴积水阳性率为42.9%;B组耳蜗内淋巴积水阳性率为13.3%,前庭内淋巴积水阳性率为66.7%。B组4例梅尼埃病发作期患者(例3、例5、例6、例14)耳蜗内淋巴积水阳性率为50%,前庭内淋巴积水阳性率为100%。B组前庭内淋巴积水阳性率高于A组。结论:梅尼埃病患者临床特征与MRI扫描诊断阳性率相关,发作期距扫描时间近或处于发作期患者MRI检查的阳性率高。
[Abstract]:Objective: to investigate the correlation between endolymphatic space imaging and clinical features (from the end of the last vertigo attack to the MRI scan time) in patients with Meniere's disease. Methods: Twenty-nine ears of 26 patients with Meniere's disease were divided into group A and group B. In group A, there was no vertigo attack on MRI scan and 14 days after the end of the last vertigo attack. In group B, 12 patients were in the period of vertigo attack or 鈮，

本文编号：1996026