气温骤降前后慢性阻塞性肺疾病患者免疫情况的变化

发布时间：2016-12-19 20:11

Before and after a sudden temperature drop in patients with chronic obstructive pulmonary disease immune change in circumstances
Xu de-hua1 xia jia-hui2 li-juan3 .Hui Zhou Hospital of Traditional Chinese Medicine,516001,China
Objective  To explore the change of immunologic function of the COPD patient to use the monoclonal antibody immunity group fluorescence dyeing under the open air temperature change Method  The T lymphocyte subgroup determination uses the monoclonal antibody immunity group fluorescence dyeing, The seroimmunity globulin (IgG, IgA, IgM) use the agar unidirectional diffusion process    Result  After the COPD patient body temperature plummets, CD3, CD4, CD4/CD8 reduce obviously, CD8 elevates obviously, IgG, IgA, IgM reduce, compares with the control group has the significance difference (P<0.01)。compares with before and after body temperature plummets,it has no  significance difference(P>0.05) .Conclusion The body temperature plummets lead to unbalanced of the cellular immunity and the humoral immunity function of tne COPD, After the body temperature plummets compares  with before, the humoral immunity and the cellular immunity function further reduces.
[Key word] sudden temperature drop; chronic obstructive pulmonary disease; immune
慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)是一种慢性气道炎症性疾病,其反复发作将导致机体免疫系统的功能的变化。天气变化与疾病的发生、发展、传播息息相关，，此时COPD患者的免疫功能状态也将发生变化，本文以COPD病人为研究对象,检测了40例COPD患者体温骤降前后外周血T淋巴细胞亚群中的总T淋巴细胞CD3、辅助性T淋巴细胞CD4、抑制性T淋巴细胞CD8和免疫球蛋白IgG、IgA、IgM,以探讨COPD患者免疫功能在外界温度变化时的变化,提供COPD免疫治疗的理论依据。

1 资料与方法

2 结果
3 讨论
参考文献



本文编号：220481