松果体区显微解剖及相关手术入路的研究

发布时间：2018-06-17 13:22

本文选题：松果体区 + 显微解剖　；参考：《四川大学》2006年博士论文

【摘要】：目的通过对经血管灌注处理的新鲜尸头标本松果体区显微解剖的研究，进一步弄清松果体区的显微结构。比较不同手术入路下对松果体区各结构的显露特点，为临床手术入路的选择提供参考。并通过对现有手术入路的改良，进一步改善对松果体区的显露，提高松果体区肿瘤的手术效果。方法本实验分为三部分：第一部分探讨尸头标本血管灌注方法，通过比较不同灌注材料的灌注特点，筛选增塑剂邻苯二甲酸二丁酯在甲基丙烯酸甲酯中的比例，改善灌注后标本的血管弹性，制备出适合显微解剖研究的脑标本：第二部分为松果体区显微解剖研究，于×7倍手术显微镜下观察松果体区血管、神经结构、蛛网膜池。测量松果体与上、下丘间的距离，松果体与丘脑枕间的距离，双侧基底静脉间的最宽距离，，脑深部静脉丛的汇入特点，天幕上的静脉窦的回流特点，上、下丘区域的血管分布特点；第三部分为松果体区手术入路研究，模拟松果体区不同手术入路(小脑上天幕下入路、枕下经天幕入路、半球间经胼胝体后部入路、经侧脑室三角区入路、经脉络裂入路等)，比较不同手术入路的显露特点，改良经典手术入路，以进一步改善对松果体区的显露。结果用改良的甲基丙烯酸甲酯灌注法灌注的脑标本血管弹性好(增塑剂占甲基丙烯酸甲酯溶液的30％)，适合用于显微解剖研究。松果体区是四叠体池、两侧环池、胼周后池、小脑上池、中间帆池等6个
[Abstract]:Objective to study the microanatomy of the pineal region of fresh cadaveric specimens treated by vascular perfusion, and to further clarify the microstructure of the pineal region. To compare the exposure characteristics of various structures in the pineal region under different surgical approaches, and to provide reference for the selection of clinical approaches. Through the improvement of the existing surgical approach, the exposure of the pineal region was further improved, and the surgical effect of the pineal region tumor was improved. Methods the experiment was divided into three parts: in the first part, the blood vessel perfusion method of cadaveric head specimens was discussed. By comparing the perfusion characteristics of different perfusion materials, the proportion of plasticizer dibutyl phthalate in methyl methacrylate was selected. The vasoelasticity of the perfused specimens was improved, and the brain specimens suitable for microanatomy were prepared. The second part was divided into microanatomical study of the pineal region. The vessels, nerve structures and arachnoid cistern of the pineal region were observed under a 脳 7 times operation microscope. The distance between pineal gland and superior, inferior colliculus, the distance between pineal body and thalamus occipital, the widest distance between bilateral basal veins, the characteristics of deep cerebral venous plexus, the characteristics of venous sinus reflux over the tentorium were measured. The characteristics of vascular distribution in the inferior colliculus region. The third part is the study of the pineal region operative approach, which simulates the different approaches in the pineal region (suprasporal subtentorial approach, suboccipital approach via tentorium approach, interhemispheric approach via posterior corpus callosum approach). The exposure characteristics of different operative approaches were compared and the classical operative approaches were improved to further improve the exposure of the pineal region through the lateral ventricular trigonometric approach and the choroidal fissure approach. Results the vasoelasticity of the brain samples infused with modified methyl methacrylate was good (plasticizer accounted for 30% of methyl methacrylate solution) and was suitable for microanatomy. The pineal region is composed of four cisterns, including the bilateral cistern, the posterior callosal cistern, the superior cerebellar cistern, the middle sail cistern, and so on.
【学位授予单位】：四川大学
【学位级别】：博士
【学位授予年份】：2006
【分类号】：R651;R322

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