2012-2013年广州地区散发性腹泻诺如病毒流行病学调查

发布时间：2018-07-11 18:09

  本文选题：诺如病毒 + 散发性腹泻　； 参考：《热带医学杂志》2014年05期

【摘要】：目的调查2012-2013年广州市散发性腹泻诺如病毒(NoV)流行状况和流行特点。方法收集2012-2013年广州地区门急诊散发性腹泻患者粪便标本2 236份,采用荧光定量RT-PCR对采集的标本进行NoV核酸检测并初步分型,收集并分析病人的临床基本信息,分析NoV阳性检出率在不同年龄段、性别、月份季节差异,同时对NoV阳性的标本进行A组轮状病毒、B组轮状病毒、C组轮状病毒、腺病毒、札如病毒、星状病毒检测,研究其混合感染情况。结果 NoV阳性检出率为10.60%(237/2 236),以GⅡ型为主。NoV在18~40岁的青年人中检出率最高(16.47%),7~17岁少年最低(3.67%),男女检出率差异无统计学意义(P0.05)。NoV全年都可检测到,夏季为高发季节,其中7~8月份检出率最高。NoV与其他肠道病毒共感染率为14.35%(34/237),其中与A组轮状病毒共感染率最高。结论广州地区NoV夏季为高发季节。在18~40岁的青年人中检出率最高,以GⅡ型感染为主,混合感染最常见为A组轮状病毒。
[Abstract]:Objective to investigate the epidemic status and characteristics of sporadic diarrhea norovirus (Nov) in Guangzhou in 2012-2013. Methods A total of 2 236 stool samples from outpatient and emergency patients with sporadic diarrhea were collected from Guangzhou from 2012 to 2013. The samples were detected by fluorescence quantitative RT-PCR and classified into Nov nucleic acid, and the basic clinical information was collected and analyzed. The positive rate of Nov was analyzed in different age, sex, month and season. Group A rotavirus group B rotavirus group C rotavirus, adenovirus, serovar virus and stellate virus were detected. The mixed infection was studied. Results the positive rate of Nov was 10.60% (237 / 2 236). Among the young people aged 1840 (16.47%), the positive rate of Nov was the highest (16.47%). There was no significant difference between male and female (P0.05). The coinfection rate of Nov with other enterovirus was 14.35% (34 / 237) in August, and the coinfection rate with group A rotavirus was the highest. Conclusion Nov is a high incidence season in Guangzhou in summer. The detection rate of G 鈪，

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