新型肝脏管道模型的数字化制造研究

发布时间：2018-07-21 10:01

【摘要】：目的设计并制作内部管道与肝实质外形兼备的新型肝脏管道模型。方法选取一具新鲜的人体肝脏标本,肝静脉及门静脉灌注后行64排螺旋CT扫描,利用Mimics软件重建门静脉、肝静脉及肝实质三维模型。在Magic4.0软件中设计肝脏管道与肝实质外壳模具的装配结构。将设计好的模型通过快速成型机进行模型的三维打印,并进行组装形成管道铸模模具。将融化的透明果冻蜡注入铸模模具内,待蜡凝固后,除去肝实质壳模具,获得新型肝脏管道模型。结果本研究通过三维重建、快速成型及模具技术成功地制作了内部管道与肝实质外形兼备的新型肝脏管道模型。模型清晰地显示肝内管道的分布情况,位置关系,分支关系,管道直径等,快速成型管道的最小直径约为1.2 mm。由透明果冻蜡制作的肝实质外形良好,清晰透明,质地与肝实质相近。结论新型肝脏管道模型表现力丰富,容易保存。它拓展了铸型标本在医学教育,科研,临床上的应用。
[Abstract]:Objective to design and make a new hepatic conduit model with both internal conduit and hepatic parenchyma. Methods A fresh human liver sample was collected and the 3D models of portal vein, hepatic vein and hepatic parenchyma were reconstructed by Mimics software after perfusion of hepatic vein and portal vein with 64-slice spiral CT scan. The assembly structure of liver tube and liver parenchymal shell mould was designed in Magic 4.0 software. The designed model is printed by the rapid prototyping machine and assembled to form the pipe casting die. The melted transparent jelly wax was injected into the mold, and after the wax solidified, the liver parenchymal shell mould was removed and a new liver tube model was obtained. Results A new model of liver conduit with both internal duct and hepatic parenchyma was successfully made by 3D reconstruction, rapid prototyping and mould technology. The model clearly shows the distribution, location, branch, diameter, etc. The minimum diameter of rapid prototyping pipeline is about 1.2 mm. The liver parenchyma made from transparent jelly wax has good shape, clear and transparent, and is similar to liver parenchyma. Conclusion the new hepatic duct model is easy to preserve. It expands the application of cast specimen in medical education, scientific research and clinical practice.
【作者单位】：南方医科大学解剖学教研室广东省医学生物力学重点实验室;南方医科大学南方医院中华创伤骨科杂志编辑部;
【基金】：广东省自然科学基金(S2011010004179,S2011040003604) 广东省中科院全面战略合作项目(2010A090100032)
【分类号】：R322.47

【参考文献】