复方益肝灵预防抗结核药物致肝损伤的临床疗效分析

发布时间：2018-01-06 07:38

本文关键词：复方益肝灵预防抗结核药物致肝损伤的临床疗效分析　出处：《临床医学研究与实践》2016年24期 　论文类型：期刊论文

【摘要】：目的研究复方益肝灵预防抗结核药物致肝损伤的临床疗效。方法选取我中心2015年4月至2015年6月管理的80例结核病患者作为本次试验的研究对象,将参与试验的患者分为两个不同的小组,分别将其定义为对照组以及研究组,每个组别的患者均为40例。对照组患者应用一般的药物进行治疗,研究组患者采取复方益肝灵药剂对患者进行抗肝损伤治疗,治疗后,比较两个组别患者的临床疗效。结果治疗后,研究组肝功能指标明显优于对照组,研究组ALT、AST及TBIL水平均明显低于对照组,差异具有统计学意义(P0.05)。研究组未表现出明显的不良反应,对照组出现1例乏力,差异无统计学意义(P0.05)。研究组肝功能损伤的发生率明显低于对照组,差异具有统计学意义(P0.05)。结论复方益肝灵预防抗结核药物致肝损伤的临床疗效显著,可对其形成一定的保护功能,降低肝损伤的发生率,对其临床疗效的提高以及生活质量的改善也有着积极的意义,具有在临床上广泛推广的价值。
[Abstract]:Objective to study the clinical effect of compound Yiganling on preventing liver injury caused by antituberculotic drugs. Methods 80 cases of tuberculosis patients from April 2015 to June 2015 in our center were selected as the subjects of this study. . The participants were divided into two different groups, defined as control group and study group, with 40 patients in each group. Patients in control group were treated with general drugs. The patients in the study group were treated with compound Yiganling medicament for anti-liver injury. After the treatment, the clinical efficacy of the two groups of patients was compared. Results after treatment, the liver function index of the study group was significantly better than that of the control group. The levels of alt AST and TBIL in the study group were significantly lower than those in the control group (P 0.05). The incidence of liver function injury in the study group was significantly lower than that in the control group. Conclusion the clinical efficacy of compound Yiganling in preventing liver injury caused by anti-tuberculosis drugs is significant, which can form a certain protective function and reduce the incidence of liver injury. It has positive significance for the improvement of clinical curative effect and quality of life, and has the value of popularizing widely in clinic.
【作者单位】：陕西省宜川县疾病预防控制中心;
【分类号】：R52;R575
【正文快照】： 结核病是呼吸科较为常见的一种疾病,当前治疗往往通过抗结核药物。抗结核药物对于患者的身体健康也有很大的威胁的,为了降低抗结核的不良反应,本文选取2015年4月至2015年6月,我中心负责管理的80例结核病患者,研究组接受复方益肝灵药剂治疗,取得满意效果,现将具体结果报道如下

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