226例艾滋病合并马尔尼菲青霉菌病患者的影像学特征

发布时间：2018-01-12 01:19

本文关键词：226例艾滋病合并马尔尼菲青霉菌病患者的影像学特征　出处：《皮肤病与性病》2016年02期 　论文类型：期刊论文

【摘要】：目的探讨艾滋病合并马尔尼菲青霉菌病患者的影像学特征。方法回顾性分析云南省传染病专科医院收治的226例艾滋病合并马尔尼菲青霉菌病患者CT扫描和腹部超声影像学表现。结果 81.9%患者CD4+T淋巴细胞50cells/μl。82.7%患者胸部CT异常,胸部CT表现为肺野斑片状浸润阴影或局限性肺实变(45.6%)、结节影(11.9%)、毛玻璃改变(11.5%),弥漫性粟粒样病变(8.4%)、结节状肿块影(5.3%)。伴肺门或纵隔淋巴结肿大(45.1%),胸腔积液(23.5%),空洞病灶(8.0%)。90.3%患者腹部B超异常,腹部超声显示脾脏肿大(63.7%),腹腔淋巴结肿大(58.0%),肝脏肿大(20.8%),腹腔积液(13.3%)。3.5%患者头颅CT异常,表现为脑室扩张或颅内低密度影。结论艾滋病合并马尔尼菲青霉菌病多发生在CD4+T淋巴细胞50cells/μl的患者,常同时出现胸部和腹部影像学异常,少数出现头颅影像学异常。胸部影像学主要表现为斑片状浸润阴影或局限性肺实变,部分表现为结节影、毛玻璃改变、粟粒样病变、结节状肿块影。常伴肺门或纵隔淋巴结肿大,较少形成空洞病灶。腹部超声常表现为肝脾肿大和腹腔淋巴结肿大。
[Abstract]:Objective to evaluate the characteristics of patients with AIDS complicated with Penicillium marneffei disease images. Methods analysis of 226 cases of AIDS complicated with Penicillium marneffei disease patients admitted to Yunnan Infectious Disease Specialist Hospital CT scan and abdominal ultrasound imaging review. Results 81.9% patients CD4+T lymph cell 50cells/ l.82.7% patients with abnormal chest CT, chest CT showed lung patchy infiltration shadows or the limitations of consolidation of the lung nodules (45.6%), (11.9%), ground glass opacity (11.5%), diffuse miliary lesion (8.4%), nodular masses (5.3%). Patients with hilar or mediastinal lymph node enlargement (45.1%), pleural effusion (23.5%), cavitary lesion (8%).90.3% patients with abnormal abdominal ultrasound, abdominal ultrasound showed splenomegaly (63.7%), abdominal lymph nodes (58%), hepatomegaly (20.8%), ascites (13.3%).3.5% patients showed abnormal cranial CT, ventricular dilatation or intracranial low density Conclusion. Patients with AIDS complicated with Penicillium marneffei disease occurs in CD4+T lymphocytes 50cells/ l patients often have abdominal and chest radiographic abnormalities, a brain imaging abnormalities. Chest imaging manifestations were patchy infiltrates or localized pulmonary consolidation, such as nodules, ground glass change. Miliary lesion, nodular masses. With hilar or mediastinal lymph nodes, fewer cavities lesions. Abdominal ultrasound showed hepatosplenomegaly and abdominal lymph nodes.

【作者单位】：云南省传染病专科医院;昆明医科大学第一附属医院皮肤性病科;
【基金】：“十二五”艾滋病和病毒性肝炎等重大传染病防治科技重大专项——成人艾滋病适宜治疗策略研究与应用(2012ZX10001-003-001)
【分类号】：R512.91;R756
【正文快照】： 马尔尼菲青霉菌病(Penicilliosis Maneffei,PSM)是由马尔尼菲青霉菌(Penicillium Maneffei,PM)感染引起的一种致死性深部真菌病,主要感染免疫功能低下的患者,尤其是艾滋病患者。发病与竹鼠的地域分布密切相关[1],主要分布于东南亚国家以及我国南方地区(广东、广西、云南、福建

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