载药医用硫酸钙颗粒局部植骨治疗骶髂关节结核

发布时间：2018-01-14 05:28

  本文关键词：载药医用硫酸钙颗粒局部植骨治疗骶髂关节结核　出处：《中国修复重建外科杂志》2015年04期 　论文类型：期刊论文

  更多相关文章： 骶髂关节结核 医用硫酸钙 利福平缓释体 转化医学

【摘要】：目的分析医用硫酸钙与注射用利福平粉末混合植骨治疗骶髂关节结核病灶清除后骨缺损的安全性、可行性和疗效。方法回顾分析2006年8月-2010年8月采用一期病灶清除、医用硫酸钙加注射用利福平局部植骨治疗的27例骶髂关节结核患者临床资料。其中男10例,女17例;年龄16~64岁,平均35.2岁。病程1.5~16个月,平均7.5个月。病变位于左侧16例,右侧10例,双侧1例。其中伴髂窝脓肿18例,臀部脓肿6例。根据Kim分型,Ⅲ型9例,Ⅳ型18例。术前Majeed评分为(61.23±6.49)分;良4例、中19例、差4例,优良率14.81%。结果术后伤口均I期愈合,无骨盆感染、周围神经损伤、下肢深静脉血栓形成等并发症发生。26例获随访,随访时间12~24个月,平均16个月。腰骶及下肢活动、感觉均正常,无会阴感觉障碍。除1例耐多药结核患者于术后3个月局部复发,经调整抗结核药物及营养支持,应用胸腺五肽增强免疫治疗,二次病灶清除术后治愈。25例患者均于术后9~12个月植骨融合,且症状消失,病灶无复发,恢复病前工作。末次随访时Majeed评分为(92.31±3.36)分,与术前比较差异有统计学意义(t=—32.76,P=0.00);获优22例,良4例,优良率100%,与术前比较差异有统计学意义(χ2=31.93,P=0.00)。结论载有注射用利福平医用硫酸钙颗粒植骨融合是治疗骶髂关节结核病灶清除后骨缺损的安全、有效方法。
[Abstract]:Objective to analyze the safety of bone graft with medical calcium sulfate and rifampicin powder for treatment of sacroiliac joint tuberculosis after clearance. Methods one stage debridement was performed from August 2006 to August 2010. Clinical data of 27 cases of sacroiliac joint tuberculosis treated with medical calcium sulfate and rifampicin local bone grafting, including 10 males and 17 females; The mean age was 35.2 years. The course of disease was 1.5 ~ 16 months (mean 7.5 months). The lesions were located in left side in 16 cases, right side in 10 cases and bilateral side in 1 case, including 18 cases with iliac fossa abscess. There were 6 cases of hip abscess. According to Kim classification, there were 9 cases of type 鈪，

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