2013-2016年南阳市流感病原学监测结果分析

发布时间：2018-01-14 10:22

本文关键词：2013-2016年南阳市流感病原学监测结果分析　出处：《现代预防医学》2017年14期 　论文类型：期刊论文

【摘要】：目的分析南阳市2013-2016年流感病毒病原学监测结果,为科学有效地防控流感提供依据。方法采集南阳市第一人民医院流感样病例咽拭子标本,采用实时荧光定量PCR方法检测流感病毒核酸,并对流感病原学监测数据进行分析。结果 2013-2016年,共采集流感样病例标本2 592份,流感病毒核酸阳性362份,总阳性率为13.97%,各年度阳性率差异有统计学意义(χ~2=75.34,P=0.000.05);4年中,H3N2亚型流行活跃,在2014年和2015年成为优势流行株,2013年和2016年与B型、新甲型H1N1交替流行;新甲型H1N1呈低流行态势;流感病毒在各监测年份中均有一个冬季流行高峰,有2个年度出现夏季流行小高峰,以H3N2亚型流行为主;流感病毒核酸在2013年和2016年以5岁~年龄组(13.67%和35.07%)阳性率最高,2014年和2015年以15岁~和25岁~年龄组阳性率最高。结论南阳市在2013-2016年流感整体流行趋势平稳;4个年份均以冬春季流行为主,夏季偶尔出现流行小高峰,H3N2亚型在4年中流行活跃。应继续做好冬春季流感防控工作,进一步关注H3N2亚型的流行趋势和病原学变化,以研究是否有变异情况发生。
[Abstract]:Objective to analyze the results of pathogenic surveillance of influenza virus in Nanyang from 2013 to 2016, and to provide a scientific and effective basis for the prevention and control of influenza. Methods the throat swabs of influenza-like cases in the first people's Hospital of Nanyang were collected. The influenza virus nucleic acid was detected by real-time fluorescence quantitative PCR and the data of influenza etiology monitoring were analyzed. Results from 2013 to 2016, 2 592 influenza like cases were collected. The total positive rate of influenza virus nucleic acid was 13.97, and the difference was statistically significant (蠂 ~ 2 ~ (2 +) 75.34) P ~ (0.000. 05); The H3N2 subtype was active in 4 years and became the dominant epidemic strain in 2014 and 2015. The new A (H1N1) was alternately prevalent with B type on 2013 and 2013. The new A (H1N1) showed a low epidemic trend; The influenza virus has a winter epidemic peak in each surveillance year, and a small summer epidemic peak in 2 years, mainly in H3N2 subtype. The positive rates of influenza virus nucleic acid were 13.67% and 35.07% in 5-year-old group and 35.07% in 2013 and 2016 respectively. In 2014 and 2015, the positive rates were the highest in the 15 ~ and 25 ~ age groups. Conclusion the overall epidemic trend of influenza in Nanyang is stable in 2013-2016. In the four years, the main epidemic was winter and spring, and the occasional epidemic peak H3N2 subtype in summer was active in 4 years. The prevention and control of influenza in winter and spring should continue to be done well. The epidemiological trend and etiological changes of H _ 3N _ 2 subtype were further investigated to determine whether there was any variation in H _ 3N _ 2 subtype.
【作者单位】：河南省南阳市疾病预防控制中心检验科;
【分类号】：R181.8;R511.7
【正文快照】： 流行性感冒,简称流感,是由流感病毒引起的急性呼吸道传染病,主要临床表现为发热、咳嗽、咽痛、头痛、乏力、全身肌肉酸痛等症状[1]。流感病毒抗原易变异,人群普遍易感,又因经呼吸道传播导致传播速度快,各地每年都会发生不同程度的流行[2]。为了解河南省南阳市流感的流行规律和

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