HIV-1阳性的广西男男性行为者启动抗病毒治疗的相关影响因素分析

发布时间：2018-01-18 01:25

本文关键词：HIV-1阳性的广西男男性行为者启动抗病毒治疗的相关影响因素分析　出处：《中国皮肤性病学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的了解HIV-1阳性的广西男男性行为人群(men having sex with men,MSM)高效抗逆转录病毒治疗(highly active antiretroviral therapy,HAART)状况及影响因素。方法从艾滋病综合防治数据信息系统中筛查在广西随访的所有感染途径为"男男性行为"的个案所有相关信息,进行随访及数据处理,用SPSS16.0软件进行数据分析。结果共1 782例MSM HIV-1阳性患者纳入分析,已经进行HAART者1 125例,未进行HAART者657例,两组人群年龄、职业、首次确诊地点、婚姻状态、目前居住地、基线CD4+T及确诊时病程差异均有统计学意义(P均0.05),HAART可能性比较:首次确诊地点为本省(OR=1.626),外省(OR=1.0);基线CD4计数200个/μL(OR=1.0),基线CD4计数200~350个/μL(OR=0.006);职业为非学生(OR=1.269~2.676),学生(OR=1.0),病程在1年内(OR=1.0),1年以上(OR=1.015~1.989),差异均有统计学意义(P0.05)。结论 HIV-1阳性的广西MSM人群HAART覆盖率较高,需加强在外省发现HIV-1感染的MSM群体的咨询,加强学生群体的隐私和HAART服务。
[Abstract]:Objective to investigate the HIV-1 positive having sex with men in men who have sex with men in Guangxi. High active antiretroviral therapy. Methods all the cases with "male sex" were screened from the comprehensive data information system of AIDS prevention and treatment in Guangxi. The data were analyzed by SPSS16.0 software. Results 1 782 MSM HIV-1 positive patients were included in the analysis. There were 1 125 cases with HAART and 657 cases without HAART. Age, occupation, location of first diagnosis, marital status and current residence of the two groups. There were significant differences in baseline CD4 T and course of disease between two groups (P < 0.05). Comparison of the probability of HAART: the first diagnosis place was OR1.626). 1. 0. 0. The baseline CD4 count was 200 / 渭 L / L OR1. 0. 0 and the baseline CD4 count was 200 ~ 350 / 渭 L OR0. 006. The occupation was non-student 1.269 / 2.676, and the course of disease was 1.0 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1). Conclusion the HAART coverage rate of MSM population with HIV-1 positive in Guangxi is higher. It is necessary to strengthen the consultation of the MSM group that found HIV-1 infection in other provinces, and strengthen the privacy and HAART service of the student group.
【作者单位】：广西疾病预防控制中心;中国疾病预防控制中心;
【基金】：广西自然科学基金(2013GXNSFAA019234) 广西卫生厅计划课题资助项目(Z2016445)
【分类号】：R512.91
【正文快照】： 至今为止,高效抗逆转录病毒治疗(highly active antiretrovi-ral therapy,HAART)仍然是对抗艾滋病最有力的手段。近年来一系列的研究表明,早期进行HAART能更好地促进免疫重建、降低疾病的发病率和死亡率,与此同时,当体内艾滋病病毒(human immunodeficiency virus,HIV-1)降低到

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