2004-2014年保定市肾综合征出血热疫情分析

发布时间：2018-01-19 03:29

本文关键词： 肾综合症出血热流行特征疫情分析　出处：《中国病原生物学杂志》2016年04期 　论文类型：期刊论文

【摘要】：目的分析保定市2004-2014年肾综合征出血热(Hemorrhagic Fever with Renal Syndrome,HFRS)的流行特征及变化趋势,为制定防控措施提供科学依据。方法利用"中国疾病预防控制信息系统",检索保定市2004-2014年HFRS临床病例和实验室诊断病例,并采用描述流行病学方法进行统计分析;用夹夜法捕鼠,计算鼠密度及鼠种构成,对鼠肺进行汉坦病毒抗原抗体检测。结果保定市2004-2014年共报告HFRS病例465例,死亡3例,年发病率为0.38/10万。2004-2007年发病率呈下降趋势,2008-2014年波动上升。发病季节性显著,各地区发病差异有统计学意义(χ2=9.46,P0.01)。男性发病337例(0.28/10万),女性发病128例(0.10/10万),男女比例为2.63∶1。0~80岁均有发病,但主要分布在20~60岁,共病379例,占81.45%。2004-2014年共布放鼠夹97 602只,捕获鼠2 424只,鼠密度为2.48%。其中,室外的平均鼠密度为4.23%,室内平均鼠密度为1.68%,差异有统计学意义(χ2=8.86,P0.05)。2004-2014年的优势鼠种为黑线姬鼠(1004只,41.43%)、褐家鼠(779只,32.12%)和小家鼠(402只,16.57%),共占总捕获量的90.12%。2004-2014年间平均带毒率为0.98%,抗体阳性率3.21%。结论保定市属于家鼠型为主的混合型疫区,近年来HFRS疫情呈明显上升趋势,提示HFRS有潜在流行趋势和暴发的可能。
[Abstract]:Objective to analyze Fever with Renal Syndrome of hemorrhagic fever with renal syndrome from 2004 to 2014 in Baoding city. The epidemic characteristics and changing trend of HFRSs provide scientific basis for making prevention and control measures. Methods the "China Disease Prevention and Control Information system" was used. The clinical and laboratory cases of HFRS from 2004 to 2014 in Baoding City were searched and analyzed by descriptive epidemiological method. The density of mice and the composition of rat species were calculated, and the antigen and antibody of Hantavirus were detected. Results 465 cases of HFRS and 3 cases of death were reported in Baoding city from 2004 to 2014. The annual incidence rate was 0.38% / 100 000. The incidence rate in 2004-2007 showed a downward trend and fluctuated and increased from 2008 to 2014. The seasonal incidence of the disease was significant. There were statistically significant differences in the incidence among different regions (蠂 ~ 2 / 9.46 / P ~ (0.01)). There were 337 cases (0.28% / 100 000) in males and 128 cases (0.10 / 100 000) in females. The ratio of male and female was 2.63: 1.0 and 80 years old, but it was mainly distributed in 20 to 60 years old. There were 379 cases of disease. A total of 97,602 rats were placed in the rat-holder in 81.45.2004-2014, 2,424 rats were captured, and the rat density was 2.48.The average outdoor rat density was 4.23%. The average indoor rat density was 1.68, the difference was statistically significant (蠂 ~ (2) 8.86) (P 0.05). The dominant rodent species from 2004 to 2014 were 1 004 Apodemus agrarius (Apodemus agrarius). 41.43m, 779 Rattus norvegicus (32.12) and 402 mice (16.57). The average rate of carrying virus was 0.98 between 2004 and 2014, and the positive rate of antibody was 3.21. Conclusion Baoding city belongs to the mixed epidemic area of house mouse type. In recent years, the HFRS epidemic situation showed an obvious upward trend, suggesting that HFRS has a potential epidemic trend and the possibility of an outbreak.
【作者单位】：河北大学附属医院;中国人民解放军66165部队医院;保定市疾病预防控制中心;
【分类号】：R512.8;R181.3
【正文快照】： *肾综合征出血热(Hemorrhagic Fever with RenalSyndrome,HFRS)是1982年由世界卫生组组织为其统一命名的。但在我国,由于历史原因,有时仍称其为流行性出血热(Epidemic Hemorrhagic Fever,EHF)。HFRS是由汉坦病毒(Hantavirus)引起,以鼠类为主要传染源的自然疫源性疾病,临床表现

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