艾滋病并发复数菌败血症患者12例临床分析

发布时间：2018-02-02 08:06

本文关键词： 艾滋病复数菌败血症　出处：《中国皮肤性病学杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的观察艾滋病并发复数菌败血症患者临床特征和药物敏感试验结果。方法回顾性分析本院12例艾滋病并发复数菌败血症患者的合并症、炎症指标、预后情况、病原菌分布及药敏结果。结果 12例艾滋病患者有10种合并症,检测血清降钙素原(4.75±9.43)μg/L,仅5例升高,院内感染7例,死亡3例;共检出24株菌株,革兰阴性菌8株(33.3%),多重耐药的大肠埃希菌和肺炎克雷伯菌共6株,产超广谱β-内酰胺酶5株;革兰阳性菌13株(54.2%)以溶血性葡萄球菌和金黄色葡萄球菌多见。结论艾滋病合并复数菌败血症患者合并症多样,病死率高,革兰阴性菌耐药比重大,应积极预防及处理。
[Abstract]:Objective to observe the clinical characteristics and drug sensitivity test results of AIDS complicated with complex bacillary septicemia. Methods 12 cases of AIDS complicated with complex bacterial septicemia were retrospectively analyzed. Results there were 10 kinds of complications in 12 patients with AIDS. Serum calcitonin was detected in 4.75 卤9.43 渭 g / L, only 5 cases were elevated. Nosocomial infection occurred in 7 cases and death in 3 cases. A total of 24 strains were identified, 8 strains of Gram-negative bacteria were found, 6 strains of Escherichia coli and Klebsiella pneumoniae were multidrug resistant, and 5 strains produced extended-spectrum 尾 -lactamases. There were 13 Gram-positive bacteria (54.2) and most of them were Staphylococcus haemolyticus and Staphylococcus aureus. Conclusion AIDS patients with complex septicemia have multiple complications and high mortality. Gram-negative bacteria have a large proportion of drug resistance and should be actively prevented and treated.
【作者单位】：杭州市西溪医院(杭州市第六人民医院);
【分类号】：R512.91;R515.3
【正文快照】： 艾滋病患者免疫功能低下,容易发生各类机会性感染,菌血症、败血症又是艾滋病患者病情加重乃至死亡的重要原因。复数菌败血症是指在同一份血标本中检出2种以上细菌,或72h内不同血标本中检出2种以上细菌所致的败血症。复数菌败血症比单一败血症更复杂,且病死率高,可达37%~82%[1]

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