甲型H1N1流感轻症患者1年随访肺功能及临床表现

发布时间：2018-02-03 09:24

本文关键词： 流感病毒A型 HN亚型轻症肺功能　出处：《中国老年学杂志》2015年07期 　论文类型：期刊论文

【摘要】：目的探讨甲型H1N1流感对轻症患者肺功能及临床表现的长期影响。方法回访2009年确诊的甲型H1N1流感所致轻症患者48例,患者出院1年后进行门诊随访(12±1)个月进行肺功能检查、评价呼吸道症状(咳嗽、咳痰或喘息等)和体征,分析远期改变与患者甲型H1N1流感病情的关系。结果 48例甲型H1N1轻症患者恢复1年后,仍有26例(54.2%)肺功能异常,其中弥散功能障碍者占33.3%、出现小气道功能障碍者占33.3%。肺功能异常多为轻、中度改变。肺功能异常组出现呼吸道症状12例(25%),肺功能正常组出现呼吸道症状者2例(4.2%),二者比较差异具有统计学意义(P0.05)。患者出院1年后肺功能改变与患病时病情轻重无显著相关性(P0.05)。结论甲型H1N1流感轻症患者出院1年后仍有部分患者肺功能异常,伴有较明显的呼吸道症状。应重视对这些患者的监测和随访,进而指导患者进行康复治疗。
[Abstract]:Objective to investigate the long-term impact of influenza H1N1 on pulmonary function in patients with mild and clinical manifestations. Methods 48 patients visit diagnosed in 2009 H1N1 influenza caused by mild patients, patients were discharged from the hospital outpatient follow-up after 1 years (12 + 1) pulmonary function test months, evaluation of respiratory symptoms (cough, expectoration or wheezing) and signs, relationship analysis and long term changes in patients with H1N1 influenza patients. Results 48 cases of patients with mild influenza a H1N1 recovery after 1 years, there are still 26 cases (54.2%) pulmonary function abnormalities, including diffuse dysfunction accounted for 33.3%, the emergence of small airway dysfunction accounted for 33.3%. pulmonary function abnormalities were mild and moderate pulmonary changes. The function of abnormal respiratory symptoms in 12 cases (25%), 2 cases of normal lung function group had respiratory symptoms (4.2%), a statistically significant difference between the two groups (P0.05). Patients were discharged after 1 years without significant changes in lung function and disease severity A correlation (P0.05). Conclusion after a 1 year discharge from influenza a H1N1 influenza, some patients still have abnormal pulmonary function and respiratory symptoms. We should pay attention to monitoring and follow-up of these patients, and guide them to rehabilitation.

【作者单位】：吉林大学第一医院呼吸科;
【分类号】：R511.7
【正文快照】： 新型甲型H1N1流感病毒于2009年引起全球性流感大流行,其中部分患者出现重症肺炎、急性呼吸窘迫综合征(ARDS),导致严重的肺部损害甚至死亡。重症肺炎及ARDS患者恢复后,常会遗留不同程度的肺部病变,影响患者呼吸功能,对患者的健康和生活质量造成不利的影响,但甲型H1N1流感轻症患

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