柳州市吸毒人群HIV、HCV和梅毒感染状况及影响因素分析

发布时间：2018-02-07 14:40

本文关键词： HIV 肝炎丙型梅毒　出处：《中华疾病控制杂志》2015年12期 　论文类型：期刊论文

【摘要】：目的了解柳州市吸毒人群的人口学特征、人类免疫缺陷病毒(human immunodeficiency virus,HIV)、丙型肝炎病毒(hepatitis C virus,HCV)和梅毒感染状况及其影响因素,为吸毒人群疾病防控工作提供科学依据。方法采用面对面问卷调查,并采集静脉血进行HIV、HCV和梅毒抗体检测。结果 HIV、梅毒和HCV感染率分别为10.0%、13.0%和69.0%。多因素分析显示,共用针具的吸毒者感染HIV的风险是未共用针具者的4倍以上(P0.001,OR=4.66,95%CI:2.32~9.37),未参与社区药物维持治疗/清洁针具交换的吸毒者感染HIV的风险比参与社区药物维持治疗/清洁针具交换者高2倍多(P=0.031,OR=2.35,95%CI:1.08~5.09);女性比男性更易感染梅毒(P=0.003,OR=2.57,95%CI:1.39~4.74);31~40岁相对≤30岁感染HCV可能性大(P0.001,OR=8.34,95%CI:3.42~20.30);≥41岁也较≤30岁感染可能性大(P0.001,OR=7.59,95%CI:3.25~17.76),共用针具以及注射吸毒也都是HCV感染的独立危险因素(P=0.013,OR=2.86;P0.001,OR=14.12)。结论加强对吸毒人群的行为干预和健康教育是预防艾滋病、梅毒以及丙肝感染的重点。
[Abstract]:Objective to understand the demographic characteristics of drug users in Liuzhou City, human immunodeficiency virus (human immunodeficiency, virus, HIV), hepatitis C virus (hepatitis C, virus, HCV) and syphilis infection situation and its influencing factors, and provide scientific basis for disease prevention and control work of drug addicts. Methods a face-to-face questionnaire survey, and blood samples were collected to detect HIV. HCV and syphilis antibodies. Results HIV, rate of syphilis and HCV infection were 10%, 13% and 69.0%. multi factor analysis showed that the needle sharing drug risk of HIV infection is not the needle sharing of more than 4 times (P0.001, OR=4.66,95%CI:2.32~9.37), did not participate in community drug treatment of HIV infection risk / Qingjiezhenju the exchange of drug addicts maintenance treatment / Qingjiezhenju exchange were more than 2 times higher than the drugs involved in the community (P=0.031, OR=2.35,95%CI:1.08~5.09); women are more prone to syphilis infection than men (P=0.003, OR= 2.57,95%CI:1.39~4.74; 31~40) relatively less than 30 years the possibility of HCV infection (P0.001, OR=8.34,95%CI:3.42~20.30); more than 41 years old are more than 30 years the possibility of infection (P0.001, OR=7.59,95%CI:3.25~17.76), sharing needles and injecting drug use are independent risk factors of HCV infection (P=0.013, OR=2.86; P0.001, OR=14.12). Conclusion behavioral intervention for drug addicts and health education to prevent AIDS, syphilis and HCV infection.

【作者单位】：柳州市疾病预防控制中心性病艾滋病防治科;安徽医科大学公共卫生学院流行病与卫生统计学系;
【基金】：广西科学研究与技术开发计划项目(桂科攻1298003-1-2) 柳州市应用技术研究与开发计划(2011J030201)
【分类号】：R512.91

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