大学生群体肺结核患病的流行病学研究,以广西大学大学生为研究案例

发布时间：2018-02-09 03:23

本文关键词： 大学生肺结核流行特征广西大学　出处：《基因组学与应用生物学》2017年06期 　论文类型：期刊论文

【摘要】：大学是年轻人群体较为密集的场所,人员的流动性频繁(高),而结核病具有传染性强和病程长等特点,是高校传染病疫病的重要防控项目之一。为了深入了解高校校园的结核病流行特征,提供全面的、完整的疫情监控、预防和治疗策略和方案,我们以广西大学2013~2016年期间在校大学生为研究对象,通过对新生入学体检病例、毕业生毕业体检病例、校医院门诊诊疗病例、广西南宁市西乡塘疾控中心反馈追踪病例及结核病密切接触者的筛查病例进行了系统的分析。结果表明,2013~2016年在校大学生结核病发病率分别为32.27/10万、49.06/10万、61.15/10万、111.57/10万,4年累计的平均发病率63.51/10万,结核病发病率呈现逐年上升的趋势。使用SPSS Statistics 20.0软件进行统计学分析,计数数据差异分析采用卡方检验,年度间差异有统计学意义(x2=23.39,p0.01);109例患者中男生多于女生,21~24岁患者占70.64%,平均年龄21.44岁,其中,通过体检筛查出的无症状病例占49.55%,因症就诊病例占50.45%,休学率为23.85%。在与55例患者的密切接触的1 717个大学生中,筛查出结核患者5例,筛出率292.21/10万。我们的研究初步发现高校大学生群体中具有较高的无症状结核病例发生,这部分患者是潜在的结核病传染源,推测这可能是引起广西大学校园大学生结核病发病率上升的主要原因。由此,我们认为主动筛查发现无症状结核病患者是控制高校结核病传染源和降低在校大学生结核发病率重要的方法和措施。
[Abstract]:The university is the groups of young people more intensive sites, frequent staff mobility (high), and has the characteristics of strong infectious tuberculosis and long duration, is one of the most important infectious diseases prevention and control project in Colleges and universities. The epidemic characteristics of tuberculosis in the university campus in order to understand, to provide comprehensive, complete epidemic monitoring, prevention and treatment strategies our school in Guangxi University and, during the period of 2013~2016 students as the research object, through the case of entrance examination, graduation examination cases, the hospital outpatient medical records, screening cases in Guangxi Nanning City CDC Xixiang Tang feedback cases and close contacts of TB are systematically analyzed. The results show that the 2013~2016 students in tuberculosis the incidence rate was 32.27/10 million, 49.06/10 million, 61.15/10 million, 111.57/10 million, the average annual incidence rate of 4 a total of 63.51/10 million, tuberculosis The disease incidence is rising year after year. Using SPSS Statistics 20 software was used for statistical analysis, the difference analysis of count data by chi square test, there was statistical significance difference between years (x2=23.39, P0.01); in 109 cases, boys more than girls, aged 21~24 patients accounted for 70.64%, the average age of 21.44 years, which, through the screening examination the asymptomatic cases accounted for 49.55%, accounted for 50.45% of patients because of illness, drop out rate of 23.85%. in close contact with the patients with 55 of the 1717 students in the screening of 5 cases of tuberculosis patients, screening rate of 292.21/10 million. Our study has higher college students' group in asymptomatic tuberculosis cases, this some patients are a potential source of infectious tuberculosis, speculate that this may be caused by an increased incidence of tuberculosis among college students in campus of Guangxi University is the main reason. Thus, we think the main dynamic screening found no disease Tuberculosis patients are the important methods and measures to control the source of tuberculosis infection in Colleges and universities and to reduce the incidence of College Students' tuberculosis.

【作者单位】：广西大学医院;
【基金】：广西大学医院资助
【分类号】：R181.3;R52

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