T淋巴细胞亚群与带状疱疹临床特征的相关分析

发布时间：2018-02-25 08:18

本文关键词： 带状疱疹 T淋巴细胞免疫　出处：《广东医学》2017年S2期 　论文类型：期刊论文

【摘要】：目的探讨各型T淋巴细胞亚群在带状疱疹患病中所起的作用。方法收集、统计确诊的带状疱疹住院患者的相关资料,分析各型T淋巴细胞亚群与该病发病、疼痛及病程的相关性。结果在发病方面:带状疱疹组总T淋巴细胞为(63.22±9.99)%,低于对照组的(63.26±12.16)%;Th为(36.83±8.65)%,低于对照组的(37.07±9.62)%;Th/Ts为1.85±0.81,稍高于对照组的1.62±0.88;但上述均差异无统计学意义(P0.05)。而Ts为(22.50±7.33)%,对照组为(26.22±7.88)%,两组相比,差异有统计学意义(P0.05)。在带状疱疹患者的疼痛程度、病程与T淋巴细胞亚群的比较方面,T淋巴细胞亚群与该病疼痛程度的相关系数分别为0.048、0.086、0.096、0.00;与该病病程的相关系数分别为-0.104、-0.013、-0.093、-0.079,无统计学意义(P0.05)。结论带状疱疹的发病与T淋巴细胞亚群存在一定的相关性,但疼痛程度和病程尚不能确定与T淋巴细胞亚群间存在相关性。
[Abstract]:Objective to investigate the role of T lymphocyte subsets in herpes zoster. Results the total T lymphocytes in the herpes zoster group were 63.22 卤9.99g and 63.26 卤12.16 Th were lower than those in the control group (36.83 卤8.65) and lower than that in the control group (37.07 卤9.62 卤0.81), slightly higher than that in the control group (1.62 卤0.88), but there was no significant difference between the two groups. The ts was 22.50 卤7.33 in the control group and 26.22 卤7.88 in the control group. The difference was statistically significant (P 0.05). The degree of pain in patients with herpes zoster was higher than that in patients with herpes zoster. The correlation coefficients between T lymphocyte subsets and pain degree of the disease were 0.0488 ~ 0.086 ~ 0.096 ~ 0.00and -0.104 ~ 0.013 ~ -0.093 ~ (-0.079), respectively. Conclusion the incidence of herpes zoster and the incidence of T herpes zoster have no statistical significance (P < 0.05), and the correlation coefficient with disease course is -0.104% -0.013% -0.093% -0.093% -0.079, respectively. Conclusion the incidence of herpes zoster is associated with the incidence of T zoster. Lymphocyte subsets have some correlation. However, the degree of pain and the course of the disease can not be determined with T lymphocyte subsets.
【作者单位】：广州医科大学附属第三医院皮肤科;
【分类号】：R752.12

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