维持性血液透析患者感染乙型肝炎和丙型肝炎病毒的危险因素分析

发布时间：2018-03-04 20:40

本文选题：维持性血液透析　切入点：乙型肝炎　出处：《中华医院感染学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的分析维持性血液透析患者感染乙型肝炎和丙型肝炎病毒的高危因素,为临床感染的预防和治疗提供借鉴依据。方法选取2014年10月-2015年10月医院临床收治的维持性血液透析患者368例为研究对象,分析维持性血液透析患者的乙型肝炎和丙型肝炎病毒感染情况、导致感染的危险因素及相关临床特点。结果共39例患者发生感染,感染率为10.60%;年龄、住院时间、透析总次数、肝炎病史、透析器复用是导致维持性血液透析患者肝炎病毒感染的独立危险因素(P0.01);感染患者的血红蛋白、血清白蛋白均低于非感染患者,感染患者C-反应蛋白、丙氨酸转氨酶和天冬氨酸转氨酶均高于非感染患者,感染患者的各项淋巴细胞亚群指标均低于非感染患者,组间上述指标比较,差异均有统计学意义(P0.05)。结论维持性血液透析患者肝炎病毒感染较为严重,危险因素较多,患者遭受感染后临床特点主要表现为营养状况下降、肝脏受损情况加剧、机体免疫能力低下等。
[Abstract]:Objective to analyze the risk factors of hepatitis B and hepatitis C virus infection in maintenance hemodialysis patients. Methods 368 patients with maintenance hemodialysis admitted in our hospital from October 2014 to October 2015 were selected as subjects. To analyze the infection of hepatitis B and hepatitis C virus in maintenance hemodialysis patients, the risk factors of infection and related clinical characteristics were analyzed. Results 39 patients developed infection, the infection rate was 10.60%, age, length of stay in hospital, total number of dialysis, Hepatitis history, dialyzer reuse is an independent risk factor for hepatitis virus infection in maintenance hemodialysis patients (P0.01), hemoglobin and serum albumin in infected patients are lower than those in non-infected patients, and C-reactive protein in infected patients. The levels of alanine aminotransferase and aspartate aminotransferase were higher than those of non-infected patients, and the lymphocyte subsets of infected patients were lower than those of non-infected patients. Conclusion Hepatitis virus infection in maintenance hemodialysis patients is more serious and the risk factors are more. The main clinical features of the patients after infection are the decrease of nutritional status and the exacerbation of liver damage. Low immune function, etc.
【作者单位】：安阳市人民医院肾内科;
【分类号】：R512.6

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