维持性透析患者感染丙肝病毒危险因素logistic回归分析

发布时间：2018-03-14 00:14

本文选题：腹膜透析　切入点：血液透析　出处：《中华医院感染学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的调查维持性腹膜透析及血液透析患者丙肝感染情况,并探讨血液透析患者丙肝感染的危险因素。方法回顾性分析2013年-2016年因终末期肾病在医院规律行透析治疗的患者208例的临床资料,将其中接受维持性腹膜透析的83例患者分为A组,将接受维持性血液透析的125例患者分为B组;比较两组患者感染率,并分析其危险因素。结果 A组丙肝感染率2.41%,B组丙肝感染率13.60%,A组丙肝感染率显著低于B组(P0.05);多因素logistic回归分析结果显示,透析时间、合并症、蛋白摄入量、C-反应蛋白水平和白蛋白水平是维持性血液透析患者丙肝感染的独立危险因素(P0.05)。结论与维持性腹膜透析相比,血液透析丙肝感染的风险更高;临床应加强透析管理,积极处理患者的合并症,改善患者的营养状态和微炎症状态,以降低丙肝感染率。
[Abstract]:Objective to investigate hepatitis C infection in patients with maintenance peritoneal dialysis and hemodialysis. The risk factors of hepatitis C infection in hemodialysis patients were investigated. Methods the clinical data of 208 patients who were treated regularly in hospital from 2013 to 2016 due to end-stage nephropathy were analyzed retrospectively. Among them, 83 patients undergoing maintenance peritoneal dialysis were divided into group A and 125 patients received maintenance hemodialysis into group B. the infection rates of the two groups were compared. Results the infection rate of hepatitis C in group A was significantly lower than that in group B (P 0.05). Protein intake, C-reactive protein level and albumin level are independent risk factors of hepatitis C infection in maintenance hemodialysis patients. Conclusion compared with maintenance peritoneal dialysis, the risk of hepatitis C infection in hemodialysis patients is higher, and dialysis management should be strengthened clinically. In order to reduce the infection rate of hepatitis C, we should deal with the complications and improve the nutritional status and microinflammation of the patients.
【作者单位】：郑州大学附属南阳医院南阳市中心医院血液内科;郑州大学附属南阳医院南阳市中心医院肾病风湿免疫科;
【基金】：河南省医学科技攻关计划项目(201402H103)
【分类号】：R512.63;R692

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