2型糖尿病患者肺炎克雷伯菌感染败血症的临床特征分析

发布时间：2018-03-15 08:04

本文选题：型糖尿病　切入点：肺炎克雷伯菌　出处：《中华医院感染学杂志》2017年22期 　论文类型：期刊论文

【摘要】：目的探索2型糖尿病并发肺炎克雷伯菌感染致败血症的临床特征与生存状况。方法选取2013年1月-2016年12月医院接受治疗的114例肺炎克雷伯菌感染所导致的败血症患者为研究对象,将其中57例2型糖尿病患者设为试验组,其余无2型糖尿病患者57例设为对照组,比较两组患者血浆糖化血红蛋白及白细胞水平、肾功能水平、预后不良发生率、并发症、治愈率及病死率。结果试验组患者的白细胞计数与对照组比较,差异无统计学意义;试验组患者的糖化血红蛋白水平低于对照组,差异有统计学意义(P0.05);试验组重度肾功能障碍患者多于对照组,差异有统计学意义(P0.05);试验组中所患胆道疾病、脂肪肝、肿瘤以及脓肿等并发症的患者多于对照组,差异有统计学意义(P0.05);试验组患者的治疗结局不良发生率高于对照组,差异有统计学意义(P0.05);两组患者治愈率比较,差异无统计学意义;试验组患者病死率高于对照组,差异有统计学意义(P0.05)。结论 2型糖尿病并发肺炎克雷伯菌感染致败血症患者的临床症状更为严重,易引发多种并发症且死亡率较高,有效的临床治疗是解决预后问题的有效途径。
[Abstract]:Objective to investigate the clinical features and survival status of septicemia caused by Klebsiella pneumoniae infection in type 2 diabetes mellitus. Methods 114 cases of septicemia caused by Klebsiella pneumoniae infection were selected from January 2013 to December 2016. The patient was the subject of the study. 57 patients with type 2 diabetes mellitus were divided into experimental group and 57 patients without type 2 diabetes mellitus as control group. Plasma glycosylated hemoglobin and leukocyte levels, renal function level, incidence of poor prognosis and complications were compared between the two groups. Results there was no significant difference in leukocyte count between the patients of the test group and the control group, and the level of glycosylated hemoglobin in the patients in the test group was lower than that in the control group. The difference was statistically significant (P 0.05); the number of patients with severe renal dysfunction in the trial group was more than that in the control group (P 0.05); the number of patients with biliary diseases, fatty liver, tumor and abscess in the trial group was more than that in the control group. The difference was statistically significant (P 0.05), the incidence of adverse outcome in the trial group was higher than that in the control group, and the difference was statistically significant (P 0.05). There was no significant difference in the cure rate between the two groups, and the mortality of the patients in the trial group was higher than that in the control group. Conclusion the clinical symptoms of patients with septicemia caused by Klebsiella pneumoniae infection in type 2 diabetes mellitus are more serious. Effective clinical treatment is an effective way to solve the problem of prognosis.
【作者单位】：浙江中医药大学;杭州市师范大学附属医院内分泌科;杭州市师范大学附属医院呼吸科;
【分类号】：R515.3;R587.1

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