卡介菌素和结核菌素纯蛋白衍生物在学校体检筛查结核病中的应用

发布时间：2018-03-21 08:48

  本文选题：卡介苗　切入点：结核菌素试验　出处：《中国学校卫生》2016年09期 　论文类型：期刊论文

【摘要】：目的比较卡介菌素纯蛋白衍生物(BCG-PPD)和结核菌素纯蛋白衍生物(TB-PPD)在学校体检筛查结核病中的效果,为学校结核病防控工作提供参考。方法对2013年和2014年的石家庄市鹿泉区中小学新入学学生使用不同的PPD试验进行筛查,对2种方法试验阳性率进行比较。结果共有10 261名学生接受了BCG-PPD试验,阳性学生913名,阳性率为8.90%;11 252名学生接受了TB-PPD试验,阳性学生457名,阳性率为4.06%,2种试验组间阳性率差异有统计学意义(χ~2=210.521,P0.01)。2种试验方法不同性别、地区、年级新生阳性率差异均有统计学意义(P值均0.05)。结论 BCG-PPD接种阳性率高于TB-PPD接种阳性率,但在筛查出胸部X线异常及确诊活动性肺结核患者方面相关不明显。在学校结核病筛查中建议采用TB-PPD方法。
[Abstract]:Objective to compare the effects of BCG-PPDs of BCG-PPDs and TB-PPDs of BCG-PPDs on the screening of tuberculosis in school physical examination. Methods in 2013 and 2014 in Luquan District, Shijiazhuang City, new students in primary and secondary schools were screened by different PPD tests. The positive rate of the two methods was compared. Results A total of 10 261 students accepted BCG-PPD test, 913 positive students, the positive rate was 8. 90% 11 252 students accepted the TB-PPD test, 457 positive students. The difference of positive rate between the two groups was statistically significant (蠂 ~ (2 +) 210.521 ~ (1) P 0.01 ~ (2)) test methods. There were significant differences in the positive rates of BCG-PPD and freshmen (P < 0.05). Conclusion the positive rate of BCG-PPD inoculation is higher than that of TB-PPD, and the positive rate of BCG-PPD is higher than that of TB-PPD (P < 0.05). However, there was no significant correlation in the screening of abnormal chest X-ray and the diagnosis of active pulmonary tuberculosis. TB-PPD method is recommended in the screening of tuberculosis in schools.
【作者单位】： 河北省石家庄市鹿泉区疾病预防控制中心;石家庄市疾病预防控制中心;
【分类号】：R52
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本文编号：1643118