医院获得性屎肠球菌血流感染患者的临床特征及耐药性分析

发布时间：2018-03-30 23:40

本文选题：屎肠球菌　切入点：血流感染　出处：《中华医院感染学杂志》2017年23期

【摘要】：目的通过分析医院获得性屎肠球菌血流感染的临床分布特征和耐药情况,为该病的防治提供参考。方法收集医院2011年1月-2015年12月165例诊断为医院获得性屎肠球菌血流感染患者的临床资料,对患者的科室分布、基础疾病、感染来源和分离菌株的药物敏感性进行统计分析。结果共纳入医院获得性屎肠球菌血流性感染患者165例,其中内科病房69例占41.82%,外科病房49例占29.70%,重症监护室47例占28.48%,消化内科32例占19.39%,肝胆外科19例占11.52%;基础疾病以恶性实体肿瘤82例占49.70%最多见;最主要的感染来源为腹腔感染共63例占38.18%;屎肠球菌对替考拉宁和利奈唑胺均敏感,对万古霉素的耐药率为4.38%。结论医院获得性屎肠球菌血流感染患者多见于重症监护室和消化内科,治疗可选用万古霉素、替考拉宁或利奈唑胺。
[Abstract]:Objective to analyze the clinical distribution and drug resistance of hospital acquired Enterococcus faecium. Methods from January 2011 to December 2015, 165 patients diagnosed as nosocomial Enterococcus faecium blood stream infection were collected. Results 165 patients with nosocomial Enterococcus faecium were included in the study. 69 cases in internal medicine ward accounted for 41.82%, 49 cases in surgical ward accounted for 29.70%, 47 cases in intensive care unit accounted for 28.48 cases, 32 cases in digestive department accounted for 19.39%, 19 cases in hepatobiliary surgery accounted for 11.52%, 82 cases of malignant solid tumor accounted for 49.70% of basic diseases. The main source of infection was intraperitoneal infection in 63 cases (38. 18%). Enterococcus faecium was sensitive to teicoplanin and linazolamine. Conclusion Hospital acquired Enterococcus faecium blood flow infection is more common in intensive care unit and digestive department. Vancomycin, teicoplanin or linazolamide can be used for the treatment of vancomycin.
【作者单位】：承德医学院附属医院呼吸内科;解放军总医院呼吸科;解放军总医院感染管理与疾病控制科;
【基金】：军队“十二五”基金资助项目(BWS14J040)
【分类号】：R446.5;R515

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