无偿献血人群人疱疹病毒8型和巨细胞病毒及细小病毒B19感染流行情况调查

发布时间：2018-04-02 18:06

本文选题：人疱疹病毒型　切入点：人类巨细胞病毒　出处：《中华医院感染学杂志》2017年03期

【摘要】：目的调查无偿献血人群中人疱疹病毒8型(HHV-8)、人类巨细胞病毒(HCMV)和人细小病毒B19(HPVB19)感染流行情况,为提供输血筛查策略提供数据支持。方法对2015年3月-2016年3月本地区选取1 046例无偿献血者采用酶联免疫吸附法(ELISA)进行血清HHV-8、HCMV和HPVB19IgM/IgG抗体检测。结果 1 046例无偿献血者中,HHV-8、HCMV及HPVB19检测阳性率分别为16.6%、91.3%及33.0%;HHV-8、HCMV和HPVB19阳性率随年龄的增加而增加,差异有统计学意义(P0.05);女性HPVB19感染阳性率明显高于男性,两组间比较差异有统计学意义(P0.05);HCMV阳性率随文化程度的增加而减少,差异有统计学意义(P0.05);HHV-8、HCMV和HPVB19阳性率在不同职业间比较,差异有统计学意义(P0.05),其中学生HHV-8和HPVB19阳性率最低为10.7%和25.9%;公务员及企事业单位人员HCMV感染阳性率最低为87.5%;不同血型献血者HHV-8、HCMV和HPVB19阳性率,差异无统计学意义。结论HHV-8、HCMV和HPVB19在本地区存在不同程度的感染,在条件允许的情况下,对重点人群输血时需对三种病毒进行检测。
[Abstract]:Objective to investigate the prevalence of human herpesvirus 8 (HHV-8), human cytomegalovirus (HCMV) and human parvovirus B19 (HPVB19) infection in blood donors and to provide data support for blood transfusion screening strategy.Methods Serum HHV-8 HCMV and HPVB19IgM/IgG antibodies were detected by enzyme linked immunosorbent assay (Elisa) in 1 046 blood donors from March 2015 to March 2016.Results the positive rates of HCMV and HPVB19 in 1 046 free blood donors were 16.61.3% and 33.0%, respectively. The positive rates of HCMV and HPVB19 increased with the increase of age, the difference was statistically significant (P 0.05), the positive rate of HPVB19 infection in women was significantly higher than that in men.The difference between the two groups was statistically significant. The positive rate of HHV-8 and HHV-8 was decreased with the increase of education level, and the positive rates of HHV-8 and HHV-8 were compared among different occupations.The positive rates of HHV-8 and HPVB19 were 10.7% and 25.9% in students, 87.5% in civil servants, 87.5% in enterprises and institutions, and the positive rates of HHV-8 and HPVB19 in blood donors of different blood groups were not statistically significant.Conclusion HCMV and HPVB19 of HHV-8 have different degrees of infection in this area. When blood transfusion is carried out in key population, three kinds of viruses should be detected.
【作者单位】：郑州大学附属郑州中心医院输血科;河南省人民医院输血科;郑州大学附属郑州中心医院检验科;郑州市第三人民医院检验科;
【基金】：河南省医学科技攻关计划项目(201412088)
【分类号】：R51;R181.3

【相似文献】