浙江省采取综合措施阻断经输血传播HIV的探索

发布时间：2018-04-03 21:50

  本文选题：HIV感染　切入点：输血传播　出处：《中国输血杂志》2015年08期

【摘要】：目的为阻断经输血传播HIV,提升浙江省血液安全水准。方法自2011年开展阻断经输血传播HIV项目,针对输血过程从血管到血管之不同阶段,采用系统性综合措施,包括前期的加强主动退出与保密性弃血、中期的推广血筛核酸检测和亚甲蓝血浆病毒灭活、后期的推进临床科学合理用血之自体输血。结果项目开展4年来,全省献血者中确认HIV感染快速上升趋势较前被明显遏制(P0.05),血液核酸筛查覆盖从2011年26.5%至2014年达51.2%,开展血浆病毒灭活工作血站明显增加,75%(9/12)血站其自体输血占临床用血5%,全省血液安全得以保障。结论阻断经输血传播HIV是一系统性综合举措开展以来全省未见输血感染HIV案例,血液安全水准明显提升。项目成果需持久的维护、推进和创新。
[Abstract]:Objective to prevent the transmission of HIV through blood transfusion and to raise the level of blood safety in Zhejiang Province.Methods the HIV project of blocking blood transfusion transmission was carried out in 2011. Systemic and comprehensive measures were adopted for different stages of blood transfusion from blood vessels to blood vessels, including early active withdrawal and confidentiality rejection.In the middle stage, sieve nucleic acid detection and methylene blue plasma virus inactivation were popularized, and autologous blood transfusion was carried out in the later stage.As a result, in the four years since the project began,Among the blood donors in the province, the rapid rising trend of HIV infection was significantly curbed. The nucleic acid screening coverage reached 51.2% from 2011 to 2014. The number of blood stations carrying out plasma virus inactivation work was significantly increased by 7575% 9 / 12). Autologous blood transfusion accounted for the clinical use at blood stations.Blood 5, the whole province blood security can be guaranteed.Conclusion there are no cases of blood transfusion infection with HIV in the whole province since the interruption of transfusion-transmitted HIV was carried out, and the blood safety level was improved obviously.Project results require sustained maintenance, promotion and innovation.
【作者单位】： 浙江省血液中心卫生部血液安全研究重点实验室;金华市中心血站;衢州市中心血站;
【分类号】：R512.91;R457.1

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