2014—2016年上海市闵行区病毒性腹泻病病原学监测研究

发布时间：2018-04-08 12:18

本文选题：病毒性腹泻病　切入点：监测　出处：《复旦学报(医学版)》2017年05期

【摘要】：目的了解上海市闵行区病毒性腹泻病流行特征和病原谱分布,为制定防控措施提供科学依据。方法按一定的抽样间隔随机选取2014—2016年闵行区2家监测点医院肠道门诊的腹泻病病例开展调查采样,同时用real-time PCR方法对采集的粪便标本进行轮状病毒(rotavirus,RV)、诺如病毒(norovirus,NV)、肠道腺病毒(adenovirus,AD)、星状病毒(astrovirus,AstV)、札如病毒(sapovirus,SaV)检测。结果两家医院共监测到腹泻病病例11 243例,2014—2016年分别为3 213、3 600和4 430例。803例病例的粪便标本开展病毒检测,其中309例检出阳性,检出率为38.48%;RV、NV、AD、AstV及SaV均有检出,以NV为主(207例,66.99%),其次为RV(77例,24.92%)。结论 2014—2016年上海市闵行区病毒性腹泻病感染病原以NV为主,季节高峰较为明显,应在流行季节开展针对性防治措施。
[Abstract]:Objective to understand the epidemic characteristics and pathogenic spectrum distribution of viral diarrhea in Minhang District, Shanghai, and to provide scientific basis for making prevention and control measures.Methods according to a certain sampling interval, the cases of diarrhoeal diseases in two hospitals in Minhang District from 2014-2016 were randomly selected to carry out investigation and sampling.Real-time PCR method was used to detect rotavirusof rotavirus, norovirusNVV, adenovirusadine, astrovirusof stellate virus and sapovirusSaV. at the same time, the method of real-time PCR was used to detect rotavirus, norovirusNVV, adenovirusadine, astrovirusof stellate virus.Results A total of 11 243 cases of diarrhoeal diseases were detected in feces of 3 2133600 cases and 4 430 cases of .803 cases from 2014 to 2016 in two hospitals, 309 of them were positive, and the positive rate was 38. 48% of them, both AstV and SaV were detected.NV was the main group of 66.99 cases, followed by RV(77 (24.92%).Conclusion NV is the main pathogen of viral diarrhea infection in Minhang District of Shanghai from 2014 to 2016, and the seasonal peak is obvious, so it is necessary to carry out targeted control measures in epidemic season.
【作者单位】：上海市闵行区疾病预防控制中心;复旦大学公共卫生学院流行病学教研室-公共卫生安全教育部重点实验室;
【基金】：上海市研究生教育创新计划上海市卫生和计划生育委员会科研课题(201440350)~~
【分类号】：R181.3;R512.5

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