蒲苓盆炎康联合阿奇霉素治疗解脲支原体感染及其对外周血NK细胞活性的影响

发布时间：2018-04-08 16:43

本文选题：阿奇霉素　切入点：解脲支原体　出处：《重庆医学》2017年30期

【摘要】：目的分析蒲苓盆炎康联合阿奇霉素治疗解脲支原体感染患者的疗效以及其对外周血自然杀伤(NK)细胞活性的影响。方法选取2013年3月至2016年12月该院收治的125例解脲支原体感染患者,分为阿奇霉素组(n=41)、蒲苓盆炎康组(n=42)与联合组(n=42),阿奇霉素组服用单一阿奇霉素片治疗,蒲苓盆炎康组采用蒲苓盆炎康治疗,联合组采用阿奇霉素联合蒲苓盆炎康治疗。比较3组的治疗效果及复发情况,检测治疗后3组患者外周血NK细胞的活性并进行比较。结果阿奇霉素组治疗有效率达63.4%,复发率达87.2%,蒲苓盆炎康组治疗有效率达66.7%,复发率达84.4%,联合组治疗有效率与复发率分别为92.9%、18.5%;阿奇霉素组与蒲苓盆炎康组比较,差异无统计学意义(P0.05),联合组与其他两组比较,差异均有统计学意义(P0.05);治疗后3组外周血NK细胞活性比较,联合组明显高于其他两组,差异具有统计学意义(P0.05)。结论口服蒲苓盆炎康联合阿奇霉素治疗解脲支原体阳性感染比单独治疗效果好,其治疗机制可能与提高外周血NK细胞活性有关。
[Abstract]:Objective to analyze the efficacy of Pulingpenyan Kang combined with azithromycin in the treatment of Ureaplasma Urealyticum infection and its effect on NK cell activity in peripheral blood.Pulingpenyan Kang group was treated with Pulingpenyan Kang, and the combined group with azithromycin combined with Pulingpenyan Kang.The therapeutic effect and relapse of the three groups were compared, and the NK cell activity in peripheral blood of the 3 groups was detected and compared after treatment.Conclusion the treatment of Ureaplasma Urealyticum positive infection by oral administration of Pulingpenyan Kang combined with azithromycin is better than that of single treatment, and its therapeutic mechanism may be related to the increase of NK cell activity in peripheral blood.
【作者单位】：山东省临沂市妇女儿童医院生殖科;
【分类号】：R691.3

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