上海市HIV抗体阴性MSM人群HBsAg和HCVAb阳性率及其影响因素调查

发布时间：2018-04-11 23:02

本文选题：HIV + 肝炎病毒　；参考：《中华疾病控制杂志》2015年12期

【摘要】：目的了解上海市艾滋病病毒(HIV)抗体阴性的男男性行为人群(men who have sex with men,MSM)中乙型肝炎病毒(hepatitis B virus,HBV)和丙型肝炎病毒(hepatitis C virus,HCV)感染现况及其影响因素。方法以上海市为现场招募HIV抗体阴性的MSM人群,收集人口学及行为学信息,进行HBV表面抗原(hepatitis B surface antigen,HBs Ag)和HCV抗体(hepatitis C surface antibody,HCVAb)检测。结果共招募983名HIV抗体阴性MSM,HBs Ag阳性率为10.8%(95%CI:9.1%~12.5%),HCVAb阳性率为0.2%。多因素Logistic回归分析显示,少数民族的HBs Ag阳性率高于汉族(OR=3.04,95%CI:1.23~7.52),而大学及以上文化程度者的HBs Ag阳性率则低于初中及以下文化程度者(OR=0.39,95%CI:0.22~0.70)。结论上海市HIV抗体阴性MSM的HBV感染率较高而HCV感染率与一般人群接近,提示有必要加强MSM人群特别是少数民族和低学历者的乙型肝炎相关健康宣教乃至HBV免疫接种等预防措施。
[Abstract]:Objective to investigate the prevalence and risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in men who have sex with men who have sex with who have sex with (MSM) in Shanghai.Methods MSM samples with negative HIV antibody were recruited from Shanghai, and demographic and behavioral information were collected. HBV surface antigen hepatitis B surface antigenin HBs Agand HCV antibody hepatitis C surface antibody were detected.Results the positive rate of HIV antibody negative HIV HBs Ag was 10.8%, 95% and 12.5% respectively. The positive rate of HCV-Ab was 0.2%.Multivariate Logistic regression analysis showed that the positive rate of HBs Ag in ethnic minorities was higher than that in Han nationality (3.04%, 95% CI: 1.23 + 7.52%), while the positive rate of HBs Ag in those with higher education level was lower than that of those with junior high school or lower education level (0.39%) and 0.22% (0.22%) 0.70%.Conclusion the HBV infection rate of MSM with HIV antibody negative in Shanghai is high, but the infection rate of HCV is close to that of the general population, which suggests that it is necessary to strengthen the preventive measures such as hepatitis B related health education and HBV vaccination among MSM population, especially among minority nationalities and people with low educational background.
【作者单位】：复旦大学公共卫生学院流行病学教研室公共卫生安全教育部重点实验室;上海市虹口区疾病预防控制中心性病艾滋病科;上海市徐汇区疾病预防控制中心性病艾滋病科;上海心生志愿者组织;上海市静安区疾病预防控制中心性病艾滋病科;上海市闵行区疾病预防控制中心性病艾滋病科;上海市疾病预防控制中心性病艾滋病科;
【基金】：“十二五”国家科技重大专项(2012ZX10001007-006)
【分类号】：R512.91

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