2012—2014临海市发热伴血小板减少综合征流行特点及病原学监测结果分析

发布时间：2018-04-12 00:22

本文选题：发热伴血小板减少综合征(SFTS) + 流行特点　；参考：《中国病原生物学杂志》2015年03期

【摘要】：目的分析2012-2014年临海市发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome,SFTS)流行特点及病原学监测结果,为临海市SFTS防控策略的制定提供依据,同时为其他低度流行区的SFTS防控提供参考。方法应用描述流行病学方法分析临海市2012-2014年SFTS病例特征及病原学监测结果。结果2012年临海市首次报告SFTS,到2014年出现一次集中于局部地区的流行,发病率较2012年显著上升(P0.05);病例发生主要集中在4-5月份,只有1个发病高峰;患者中男性4例,男性发病率为0.649/10万,女性5例,女性发病率为0.881/10万,男女SFTS发病率差异无统计学意义(P0.05);患者年龄主要集中在50-70岁之间,占77.8%;职业以农民为主,占88.9%;报告单位以本地综合性医疗机构为主,占77.8%。就诊不及时及诊断延误是造成SFTS病死率较高的主要原因。病例分布及病原学监测表明临海市的SFTS疫情属于局部暴发流行,66.7%的患者均来自白水洋镇黄坦乡或有此地野外暴露史,在患者居住地周围采集到的蜱虫标本检测3组布尼亚病毒核酸阳性,说明存在自然疫源地。结论临海市SFTS疫情具有明显的地域性和季节性,2014年发病率有升高趋势,并且存在自然疫源地,高龄农民为高危人群,SFTSV仍为主要病原,就诊不及时及诊断的延误是造成SFTS病死率高的主要原因。
[Abstract]:Objective to analyze the epidemic characteristics and etiological monitoring results of severe fever with thrombocytopenia syndrome (SFTs) in Linhai City from 2012 to 2014, so as to provide a basis for the formulation of SFTS prevention and control strategy in Linhai City, and to provide a reference for the prevention and control of SFTS in other low epidemic areas.Methods descriptive epidemiological method was used to analyze the characteristics of SFTS cases and the results of etiological surveillance in Linhai from 2012 to 2014.Results the SFTS was first reported in Linhai City in 2012, and there was a local epidemic in 2014. The incidence of SFTS was significantly higher than that of 2012. The incidence of SFTS was mainly concentrated in April and April, with only one peak.The incidence rate of male was 0.649 / 10 1 million, 5 cases of female, the incidence rate of female was 0.881% / 100 000. There was no significant difference in incidence rate of SFTS between men and women (P 0.05%). The age of patients was mainly between 50 and 70 years old, accounting for 77.8%.The reporting units were mainly local comprehensive medical institutions, accounting for 77.8%.The high mortality rate of SFTS was mainly caused by the delay in diagnosis.Case distribution and etiological surveillance showed that 66.7% of the patients with SFTS in Linhai were from Huangtan Township of Baishuiyang Town or had a history of field exposure.Three groups of Bunia virus nucleic acid positive were detected in ticks collected around the patient's residence, indicating the existence of natural foci.Conclusion the epidemic situation of SFTS in Linhai City is obviously regional and seasonal, the incidence of SFTS in 2014 is increasing, and there is a natural foci, and the elderly farmers are still the main pathogens of the disease.The high mortality rate of SFTS is mainly due to the delay in diagnosis.
【作者单位】：临海市疾病预防控制中心传染病防制科;
【分类号】：R511

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