液氮联合合金钛棒治疗面部扁平疣804例临床观察

发布时间：2018-04-16 21:07

本文选题：液氮 + 合金钛棒　；参考：《九江学院学报(自然科学版)》2016年04期

【摘要】：目的比较合金钛棒和棉签蘸取液氮治疗面部扁平疣的疗效和安全性。方法将804例患者随机分为2组:A组使用合金钛棒浸泡液氮;B组棉签蘸取液氮。治疗时间原则均为一个冻融期。每2周进行复诊1次,每次进行疗效评定,同时详细记录患者的不良反应。结果治疗4周后再随访观察4周判定疗效。治疗组404例,痊愈397例,显效2例,有效1例,有效率99.1%;对照组400例,痊愈391例,显效4例,有效1例,有效99%,两组临床疗效经x~2检验,两组痊愈率(x~2=10.76,p0.01)、有效率(x~2=6.75,p0.01)差异无统计学意义。治疗组中404例患者,红斑程度为0者15例,程度为1者7例,程度为2者2例;对照组中红斑程度为0者36例,1者13例,2者7例。两组红斑程度经x~2检验p0.01,差异有统计学意义。治疗组404例患者中,有色沉13例,对照组中色沉29例,x~2检验p0.01;治疗组中有色素减退1例,对照组中有色素减退7例,x~2检验p0.01,两组之间比较差异有统计学意义。结论合金钛棒联合液氮治疗面部扁平疣效果与经典的棉签蘸取液氮治疗效果相比较,虽然两者有效率无统计学差异,但前者不良反应轻,副作用小,恢复效果好,值得临床进一步研究及推广使用。
[Abstract]:Objective to compare the efficacy and safety of titanium rods and cotton swabs in the treatment of facial verruca plana.Methods 804 patients were randomly divided into two groups: group 1: group A was soaked with titanium rods and group B was dipped with cotton swabs for liquid nitrogen extraction.The principle of treatment time is a freezing and thawing period.Every 2 weeks, the curative effect was evaluated, and the adverse reactions were recorded in detail.Results after 4 weeks of treatment, the patients were followed up for 4 weeks.In the treatment group, 404 cases were cured, 397 cases were cured, 2 cases were effective, 1 case was effective, the effective rate was 99.1, while in the control group, 400 cases were cured, 391 cases were cured, 4 cases were effective, 1 case was effective, and the effective effect was 99%.There was no significant difference between the two groups in the recovery rate and the effective rate of the two groups.In the treatment group, the erythema degree was 0 in 15 cases, 1 in 7 cases and 2 in 2 cases in the treatment group, while in the control group, the degree of erythema was 0 in 36 cases and in 13 cases in the control group.The degree of erythema in the two groups was tested by xan2 (p 0.01), and the difference was statistically significant.In the treatment group, there were 13 cases of nonferrous sedimentation and 29 cases of color sink in control group (p0.01), one case of pigmentation in treatment group and 7 cases of pigmentation in control group (p0.01), the difference between the two groups was statistically significant.Conclusion the therapeutic effect of titanium alloy bar combined with liquid nitrogen in treating facial flat warts is better than that of traditional cotton swabs dipping liquid nitrogen. Although there is no significant difference in the effective rate between the two groups, the former has the advantages of light adverse reaction, little side effect and good recovery effect.It is worthy of further clinical research and application.
【作者单位】：九江学院临床医学院皮肤科;
【分类号】：R752.52

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