吉林省2009～2014年麻疹病例含麻疹成分疫苗免疫史对临床特征的影响

发布时间：2018-04-26 05:00

  本文选题：含麻疹成分疫苗 + 免疫史　； 参考：《中国疫苗和免疫》2015年04期

【摘要】：目的分析吉林省2009~2014年麻疹病例含麻疹成分疫苗(Measles-containing Vaccine,MCV)免疫史对临床特征的影响。方法收集吉林省2009~2014年麻疹监测系统报告的麻疹确诊病例,采用描述流行病学方法分析年龄及MCV免疫史;选择实验室确诊麻疹病例,剔除免疫史不详病例后将病例分为0剂与≥1剂组,运用逻辑斯谛(Logistic)回归分析MCV免疫史对临床特征的影响。结果 Logistic回归分析结果显示,与0剂MCV免疫史麻疹病例相比,≥1剂MCV免疫史麻疹病例发生咳嗽的比值比(Odds Ratio,OR)为0.514[95%可信区间(Confidence Interval,CI)为0.369~0.714,P0.05),发生口腔黏膜斑的OR值为0.451(95%CI:0.386~0.529,P0.05),结论≥1剂MCV免疫史麻疹病例发生咳嗽和口腔黏膜斑较0剂MCV免疫史麻疹病例轻,接种MCV对降低发病风险、减轻临床症状有重要意义。
[Abstract]:Objective to analyze the effect of the history of measles vaccine measure-containing vaccine MCV on the clinical characteristics of measles cases in Jilin province from 2009 to 2014. Methods the confirmed measles cases reported by the measles Surveillance system from 2009 to 2014 in Jilin Province were collected, the age and MCV immunization history were analyzed by descriptive epidemiology method, and the laboratory confirmed measles cases were selected. The patients were divided into 0 dose group and 鈮，

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