临沧市无偿献血标本梅毒检测阳性情况分析

发布时间：2018-04-27 05:28

本文选题：无偿献血 + 标本　；参考：《皮肤病与性病》2016年06期

【摘要】：目的对临沧市无偿献血标本梅毒检测阳性情况进行分析,为制定献血者梅毒检测阳性后的屏蔽、告知和归队策略提供依据。方法对无偿献血标本分别采用2种不同厂家的TP-ELISA试剂进行检测,两次检测均为阳性的标本送市疾控中心采用TPPA和TRUST法进行检测,对不同方法的检测结果进行统计分析。结果 TP-ELISA检测阳性人群以26岁至45岁的农民和流动人口为主,在献血标本TP-ELISA法检测结果判定为阳性的标本中,有17.79%为单试剂阳性或可疑阳性标本,在TP-ELISA双试剂阳性的标本中,有17.57㳠的标本TPPA和TRUST检测均为阴性。结论梅毒抗体阳性人群在不同年龄、职业分布方面有明显的差异性,在献血者招募及梅毒防治宣传时可以此为据进行针对性的招募和宣传;不同检测试剂、方法在灵敏度、特异性方面的差异是造成血液在梅毒抗体筛查项目上淘汰的重要原因,制定科学合理的献血者筛查、归队指南是保障血液安全及避免献血者流失的必要举措。
[Abstract]:Objective to analyze the positive situation of syphilis in unpaid blood donation samples in Linchang City, and to provide evidence for establishing the screening, informing and returning strategy of syphilis positive blood donors. Methods two kinds of TP-ELISA reagents from two different manufacturers were used to detect the free blood donation samples. The positive samples were sent to the city center for disease control by TPPA and TRUST. The results of different methods were statistically analyzed. Results the majority of TP-ELISA positive people were peasants aged 26 to 45 years old and floating population. 17.79% of the blood donation samples were positive by TP-ELISA method, and 17.79% were positive with single reagent or suspicious positive samples, and 17.79% were positive with TP-ELISA double reagents. 17.57? Both TPPA and TRUST were negative. Conclusion there are significant differences in the distribution of syphilis antibody in different age and occupation, which can be used as the basis of recruitment and propaganda for blood donors and syphilis prevention and control. The difference in specificity is an important reason for the elimination of syphilis antibody screening. It is necessary to make a scientific and reasonable screening of blood donors and to return to the team to ensure the safety of blood and avoid the loss of blood donors.
【作者单位】：云南省临沧市中心血站;
【分类号】：R759.1

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