重型病毒型肝炎患者医院感染危险因素研究

发布时间：2018-04-29 23:17

本文选题：重型病毒型肝炎 + 病原菌　；参考：《中华医院感染学杂志》2015年16期

【摘要】：目的探讨重型病毒型肝炎患者医院感染病原菌分布、感染部位及危险因素,为临床重型病毒型肝炎医院感染预防控制提供依据。方法回顾性分析2006年1月-2014年1月医院收治的340例重型病毒型肝炎患者临床资料,分析发生感染患者的病原菌及感染因素,数据采用SPSS 18.0软件进行统计分析。结果共发生医院感染160例,感染率47.06%;检出病原菌主要有白色假丝酵母菌、大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌及金黄色葡萄球菌,分别占32.92%、27.08%、21.25%、13.75%、5.00%;logistic回归多因素分析结果显示,年龄、肝硬化、应用抗菌药物、免疫功能低下及侵入性操作均为重型病毒型肝炎患者发生医院感染的独立危险因素(P0.05)。结论重型病毒型肝炎患者医院感染的发生率高、病原菌种类多、感染部位广,临床治疗过程中应根据相应的危险因素规范操作避免感染的发生。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria, infection site and risk factors of nosocomial infection in patients with severe viral hepatitis, and to provide evidence for the prevention and control of nosocomial infection in patients with severe viral hepatitis. Methods the clinical data of 340 patients with severe viral hepatitis from January 2006 to January 2014 were analyzed retrospectively. The pathogenic bacteria and infection factors were analyzed. The data were analyzed by SPSS 18.0 software. Results there were 160 cases of nosocomial infection, the infection rate was 47.060.The main pathogenic bacteria were Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, which accounted for 32.922,27.080.21.250.13.755.000.The results of logistic regression analysis showed that the main pathogens were Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, respectively. Age, cirrhosis, antimicrobial use, low immune function and invasive operation were all independent risk factors for nosocomial infection in patients with severe viral hepatitis. Conclusion the incidence of nosocomial infection in patients with severe viral hepatitis is high, there are many kinds of pathogenic bacteria, and the sites of infection are wide. In the course of clinical treatment, the occurrence of infection should be avoided according to the corresponding risk factors.
【作者单位】：山东省费县人民医院感染科;山东省费县人民医院检验科;河北医科大学第三医院手外科;
【基金】：河北卫生厅重点科技研究基金资助项目(20120341)
【分类号】：R512.6

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