北京市海淀区高校结核病患者及其密切接触者筛查分析

发布时间：2018-05-04 22:32

本文选题：大学 + 结核　；参考：《中华疾病控制杂志》2017年09期

【摘要】：目的通过分析海淀区高校结核病患者及密切接触者筛查情况,为海淀区高校密切接触者筛查策略的修改提供科学依据。方法对海淀区2015年3月~2016年3月发现的高校结核患者及其密切接触者进行问卷调查,并对密切接触者均进行结核菌素试验(purified protein derivative test,PPD)及胸片检查。分析患者基本人口学特征,密切接触者人口学特征、结核感染情况及患者检出情况。结果本次研究共诊断88例结核病患者,筛查得到密切接触者3 604名。密切接触者中共检出肺结核患者16例,且均为菌阴患者,患者检出率为443.95/10万。3 604名密切接触者中,PPD强阳性率8.32%。随着PPD反应直径的增加,密切接触者中患者检出率升高,且趋势有统计学意义(x_(trend)~2=8.06,P0.001)。疫情期间密切接触者PPD强阳性率和患者检出率均高于非疫情期(均有P0.05)。结论应加强高校学生结核病的筛查,根据不同的结核病检出情况适当扩大筛查范围,从而及早发现感染者及患者,进行预防性治疗,避免高校结核病的暴发流行。
[Abstract]:Objective to analyze the screening situation of tuberculosis patients and close contacts in colleges and universities in Haidian District, and to provide scientific basis for the modification of screening strategies for close contacts in colleges and universities in Haidian District. Methods A questionnaire survey was conducted among college tuberculosis patients and their close contacts in Haidian District from March 2015 to March 2016. The patients were tested with purified protein derivative test (PPD) and chest radiographs. The basic demographic characteristics of patients, the demographic characteristics of close contacts, tuberculosis infection and patient detection were analyzed. Results A total of 88 tuberculosis patients were diagnosed in this study, and 3 604 close contacts were screened. The positive rate of PPD was 8.32 in 443.95 / 100,604 close contacts. With the increase of the diameter of PPD reaction, the positive rate of patients in close contact increased, and the trend was statistically significant. The strong positive rate of PPD and the positive rate of patients in close contact during the epidemic period were higher than those in non-epidemic period (P 0.05). Conclusion the screening of tuberculosis among college students should be strengthened and the screening scope should be expanded according to different tuberculosis detection conditions so as to detect infected persons and patients as early as possible and carry out preventive treatment so as to avoid the outbreak of tuberculosis in colleges and universities.
【作者单位】：北京大学公共卫生学院流行病与卫生统计学教研室;北京市海淀区疾病预防控制中心结核病防治科;
【分类号】：R52

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