2009-2014年济南市人群禽流感病毒感染风险分析

发布时间：2018-05-12 03:46

本文选题：禽流感 + 监测　；参考：《中国病原生物学杂志》2015年10期

【摘要】：目的综合分析济南市2009-2014年流感、禽流感和不明原因肺炎监测结果,以评估人群感染禽流感的风险。方法通过涉禽环境标本监测、职业暴露人群血清学监测、流感哨点医院监测、不明原因肺炎监测等建立禽流感监测体系。结果 2009-2014年共采集外环境标本1 151份,A型通用病毒核酸阳性率为3.04%(35/1151),其中H5阳性率为2.00%(23/1151),H9阳性率为1.04%(12/1151),未检出H7阳性标本。城乡活禽市场禽流感病毒核酸检测阳性32份,阳性率为7.10%(32/451),家禽规模化养殖场禽流感病毒核酸检测阳性3份,阳性率为0.43%(3/700),城乡活禽市场阳性率高于家禽规模化养殖场(χ2=41.347,P0.05)。不同种类环境标本中清洗禽类污水禽流感病毒核酸阳性率(8.05%)最高。采集职业暴露人群血清873份,H5N1抗体阳性率为0.34%(3/873)。4家流感哨点医院采集流感样病例鼻咽拭子标本8 291份,流感病毒分离阳性率5.61%(465/8 291),未分离到H5/H7/H9亚型毒株。2009-2014年济南市共报告不明原因肺炎12例,其中1例确诊为H5N1亚型禽流感。结论济南市涉禽环境中存在H5/H9禽流感病毒污染,职业暴露人群存在H5N1禽流感隐性感染者,不排除发生禽流感散发病例的可能,但人群发生禽流感病毒感染的风险较低。
[Abstract]:Objective to synthetically analyze the results of 2009-2014 years' influenza, avian influenza and unidentified pneumonia in Ji'nan to assess the risk of avian influenza infection. Methods avian influenza surveillance system was established through monitoring of environmental specimens of wading birds, serological monitoring of occupational exposed population, monitoring of influenza sentinel hospital, monitoring of unknown cause pneumonia and so on. The results were 2009-2014 years. The positive rate of A type general virus nucleic acid was 3.04% (35/1151), the positive rate of H5 was 2% (23/1151), the positive rate of H9 was 1.04% (12/1151), and no H7 positive specimens were detected. The positive rate of avian influenza virus nucleic acid detection in urban and rural live poultry market was 32, the positive rate was 7.10% (32/451) and avian influenza virus nucleic acid in poultry farms. The positive rate of 3 positive samples was 0.43% (3/700), and the positive rate of urban and rural live poultry was higher than that of poultry farms (x 2=41.347, P0.05). The positive rate of avian influenza virus nucleic acid (8.05%) was the highest in different kinds of environmental specimens. 873 sera were collected from occupational exposure population, and the positive rate of H5N1 antibody was 0.34% (3/873).4 home flu sentinel. 8291 specimens of nasopharynx swabs from influenza like cases were collected, the positive rate of influenza virus isolation was 5.61% (465/8 291), and 12 cases of unidentified pneumonia were reported in Ji'nan city of.2009-2014 of H5/H7/H9 subtype, of which 1 cases were diagnosed as H5N1 subtype avian influenza. The conclusion was that there were H5/H9 avian influenza virus pollution in the Ji'nan wading environment and occupational exposure people. The presence of H5N1 avian influenza infection in the group does not exclude the possibility of the outbreak of avian influenza, but the risk of avian influenza virus infection is low.

【作者单位】：济南市疾病预防控制中心;济南市天桥区疾控中心;济南市历城区疾控中心;济南市济阳县疾控中心;
【分类号】：R511.7

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