PCT和hs-CRP检测对血流感染患者诊断的价值

发布时间：2018-05-19 01:26

本文选题：降钙素原 + 超敏C反应蛋白　；参考：《浙江医学教育》2016年06期

【摘要】：目的:探讨降钙素原(PCT)定量检测和超敏C反应蛋白(hs-CRP)在血流感染患者诊断中的价值。方法:回顾性分析重症监护室204例患者的临床资料,将患者分为革兰氏阴性(G-)杆菌血流感染组和革兰氏阳性(G+)球菌血流感染组以及非感染患者组。比较各组患者PCT、hs-CRP、WBC有无差异,并且应用受试者工作特征曲线(ROC曲线)进行分析。结果:(1)G-杆菌组患者的PCT、hs-CRP水平明显高于G+球菌组和非感染患者组(P0.05)。G+球菌组患者的PCT水平高于非感染患者组(P0.05);(2)ROC曲线分析显示,G-杆菌组PCT的曲线下面积(AUC)为0.925,且PCT为3.86 ng/m L时,敏感性为91.0%,特异性为90.0%,G+球菌组PCT的曲线下面积(AUC)为0.691,且PCT为1.145 ng/m L时,敏感性为43.8%,特异性为73.3%。结论:G-杆菌血流感染所致重症患者PCT、hs-CRP水平高于G+球菌血流感染者,二者联合检测可作为危重病血流感染患者的常规监测指标。
[Abstract]:Objective: To investigate the value of calcitonin (PCT) quantitative detection and hypersensitive C reactive protein (hs-CRP) in the diagnosis of blood flow infection. Methods: the clinical data of 204 patients in ICU were analyzed retrospectively. The patients were divided into gram negative (G-) bacilli blood flow infection group and gram positive (G+) positive (G+) blood flow infection group and non infected group. PCT, hs-CRP and WBC were compared and analyzed. Results: (1) the PCT, hs-CRP level of the G- group was significantly higher than that of the G+ and non infected group (P0.05).G+ cocci group, and the PCT water level was higher than that of the non infected group (P0.05); (2) the curve analysis showed that the lever was the lever. The area under the curve (AUC) of the bacteria group PCT was 0.925, and the sensitivity was 91%, the specificity was 90% when PCT was 3.86 ng/m L, and the area under the curve of PCT in the G+ cocci group was 0.691, and the PCT was 1.145 ng/m L. The sensitivity was 43.8%. The combined detection of two can be used as a routine monitoring index for critically ill patients with bloodstream infections.
【作者单位】：平湖市第一人民医院;
【基金】：平湖市科技计划项目(编号:2015-70)
【分类号】：R515.3;R446.1

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