肺结核并发肺癌患者的临床特点和生存状况研究

发布时间：2018-05-31 06:14

  本文选题：肺结核 + 肺癌　； 参考：《中国现代医学杂志》2015年31期

【摘要】：目的观察肺结核并发肺癌患者的临床特点和生存状况,探讨影响预后的相关因素。方法回顾性分析2004年1月-2009年12月该院收治的80例肺结核并发肺癌患者的临床和影像学特征。采用Kaplan-Meier法计算各亚组1、3及5年生存率,并用Log-rank检验进行比较。采用多因素Cox比例风险回归模型进行预后分析。结果咳嗽(45.0%)是最常见的首发症状。32例(40.0%)患者的肿瘤位于左肺,39例(48.8)患者的肿瘤位于右肺,9例(11.3%)患者的肿瘤位于双肺。周围性肺癌的发生率为65.0%。最常见的病理类型是鳞癌(57.5%)。肿瘤TNM分期方面,Ⅰ、Ⅱ、Ⅲ及Ⅳ期分别占61.3%、38.8%、27.5%和11.3%。结节状团块是最常见的影像学表现,占41.3%。患者中位生存时间为27个月,1、3及5年总生存率分别为66.7%、46.8%和31.1%。肺结核处于活动期、肿瘤TNM分期为Ⅲ~Ⅳ期、结核与肿瘤病灶不是同一病灶是导致肺结核并发肺癌预后不良的独立危险因素(P0.05)。结论肺结核并发肺癌患者无特异性的临床症状,影像学检查,特别是胸部HRCT有助于早期诊断,肺结核是否活动、肿瘤TNM分期、结核与肿瘤病灶是否为同一病灶是影响患者预后的独立因素。
[Abstract]:Objective to observe the clinical features and survival status of pulmonary tuberculosis complicated with lung cancer and to explore the related factors affecting prognosis. Methods the clinical and imaging features of 80 patients with pulmonary tuberculosis complicated with lung cancer from January 2004 to December 2009 were retrospectively analyzed. The 3-year and 5-year survival rates of each subgroup were calculated by Kaplan-Meier method and compared with Log-rank test. Multivariate Cox proportional risk regression model was used to analyze the prognosis. Results 45.0) is the most common initial symptom. 32 patients with tumor located in the left lung, 39 patients with tumor located in the right lung, 9 patients with tumor located in the right lung, 11.3) patients with tumor located in both lungs. The incidence of peripheral lung cancer was 65.0. The most common pathological type is squamous cell carcinoma 57.5%. In TNM stage, 鈪，

本文编号：1958608