2009-2013年南京市流感流行病学特征分析

发布时间：2018-06-01 06:19

本文选题：流感 + 人　；参考：《中华疾病控制杂志》2017年01期

【摘要】：目的描述2009-2013年期间南京市流感的流行病学规律和特点。方法流感样本来源于流感样病例,利用逆转录聚合酶链反应确定阳性病例以及流感分型。采用Excel 2007整理数据和SPSS 19.0进行统计分析。结果 2009-2013年间,南京地区共有流感样病例17 906例,其中阳性2 990例,流感阳性率为16.7%。流感阳性率随月份、季度和年份而改变,南京阳性率高峰主要出现在秋冬季,也伴有一些夏季的高峰。甲型流感主要在夏季、秋季和冬季流行,乙型流感主要在冬季流行。2009-2013年南京优势毒株为甲型H1N1,H3N2和乙型流感。H3N2通常在秋季和夏季达到流行高峰,甲型H1N1大流行在秋季出现高峰,乙型流感主要在冬季流行。南京地区在秋季和初冬出现流行高峰,但有些年份,在夏季和初秋出现H3N2流行高峰。采用移动流行病学方法建立标准模型,一般流感在南京的流行大约持续11周,流行阈值为25.21%,流感阳性的背景率为5.82%。结论南京流感高峰通常一年发生一次,但在有些年份中,会出现两个流感高峰时期。
[Abstract]:Objective to describe the epidemiological characteristics of influenza in Nanjing from 2009 to 2013. Methods Influenza samples were collected from influenza-like cases. Positive cases and influenza typing were determined by reverse transcriptase polymerase chain reaction (RT-PCR). Excel 2007 was used to collate the data and SPSS 19.0 for statistical analysis. Results from 2009 to 2013, there were 17 906 cases of influenza in Nanjing, of which 2 990 were positive, and the positive rate of influenza was 16. 7%. The positive rate of influenza varies with months, quarters and years. The peak of positive rate in Nanjing mainly occurs in autumn and winter, and also has some peak in summer. Influenza A is mainly prevalent in summer, autumn and winter. The predominant strains of influenza B in Nanjing from 2009 to 2013 are H1N1 1 H3N2 and influenza B. H3N2 usually reach the peak in autumn and summer, and the A H1N1 pandemic peak in autumn. Influenza B is prevalent mainly in winter. The epidemic peak occurred in autumn and early winter in Nanjing area, but in some years, H3N2 epidemic peak occurred in summer and early autumn. A standard model was established by using mobile epidemiology. The prevalence of general influenza in Nanjing lasted about 11 weeks, the epidemic threshold was 25.21 and the background rate of influenza positive was 5.82. Conclusion the influenza peak in Nanjing usually occurs once a year, but in some years, there are two flu peaks.
【作者单位】：东南大学公共卫生学院流行病学教研室;南京市疾病预防控制中心急性传染病防制与学校卫生科;
【基金】：国家自然科学基金(81273143)
【分类号】：R511.7;R181.3

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