女性及其男性性伴侣HPV感染状况及型别分析

发布时间：2018-06-06 00:31

本文选题：人乳头瘤病毒 + 男性伴侣　；参考：《医学研究生学报》2017年12期

【摘要】：目的人乳头瘤病毒(HPV)感染可致宫颈癌等多种恶性肿瘤,控制HPV感染极为重要。文中旨在探讨女性及其男性性伴侣HPV感染状况基因型分布,为制定HPV防控措施提供依据。方法收集2015年12月至2016年5月在连云港市第一人民医院及连云港市东方医院皮肤科HPV阳性的110例女性患者及其男性性伴侣。采集女性患者的宫颈脱落细胞及其男性性伴侣尿道口上皮细胞,并进行HPV分型检测,对结果进行分析。结果 110例女性患者中单一型别感染患者68例(61.82%),多重型别感染患者42例(38.18%)。110例男性性伴共检测到HPV感染37例,感染率33.64%,单一型别感染23例(62.16%),多重型别感染14例(37.84%)。HPV感染的男性共检测出HPV型19种,高危HPV型别出现频次39次(65%),低危HPV型别出现频次21次(35%)。性伴双方HPV吻合率为54.05%,完全及部分吻合率均为27.03%。结论HPV感染女性的男性性伴有较高的HPV感染率且男女双方型别一致性高;对男性进行HPV干预,常规开展男性HPV检测具有重要意义。
[Abstract]:Objective Human papillomavirus (HPV) infection can cause cervical cancer and other malignant tumors. It is very important to control HPV infection. The aim of this study was to investigate the genotype distribution of HPV infection in female and male sexual partners, and to provide evidence for the prevention and control of HPV. Methods from December 2015 to May 2016, 110 female patients and their male sexual partners who were positive for HPV in the dermatology department of Lianyungang first people's Hospital and Lianyungang Oriental Hospital were collected. Cervical exfoliated cells and male sexual partner urethral orifice epithelial cells were collected from female patients. The results were analyzed by HPV typing. Results among 110 female patients, 68 patients with single type infection had 61.82% infection, and 42 patients with multiple type infection had 38.18% HPV infection. 37 cases of male sex companion were detected. The infection rate was 33.64%, 23 cases of single type infection were found to be 62.16%, and 14 cases of multiple type infection were found to have 19 HPV types, 39 times of high risk type of HPV and 21 times of frequency of 35 times of low risk type of HPV. The HPV anastomosis rate was 54.05%, and the complete and partial anastomosis rate was 27.03%. Conclusion male patients with HPV infection have higher HPV infection rate and higher type consistency between men and women. It is important to carry out HPV intervention and routine detection of male HPV in male patients with HPV infection.
【作者单位】：蚌埠医学院附属连云港市东方医院皮肤科;连云港市第一人民医院皮肤科;
【基金】：蚌埠医学院研究生科研创新计划项目(Byycx1521) 连云港市社会发展计划项目(SH1421)
【分类号】：R511

【相似文献】