原方案加中药对比换用克力芝改善HAART后免疫重建不良的临床研究

发布时间：2018-06-12 01:22

本文选题：艾滋病病人 + 高效抗反转录病毒治疗　；参考：《中国艾滋病性病》2015年08期

【摘要】：目的了解高效抗反转录病毒治疗(HAART)后,免疫重建不良的艾滋病(AIDS)病人,换用克力芝(洛匹那韦/利托那韦),或继续原HAART方案加用中药治疗,比较这两种方法对免疫重建不良AIDS病人的疗效。方法 47例免疫重建不良病人中,30例换用克力芝治疗,17例加用中药治疗,观察治疗半年后两组病人的CD+4T淋巴细胞(简称CD4细胞)水平。结果克力芝组30例病人换药半年后,CD4细胞水平较前有明显升高(P0.05),中药组17例病人加用中药半年后,CD4细胞水平较前有明显升高(P0.05),两组比较,克力芝组的CD4细胞水平较中药组升高明显(P0.05)。结论中药及克力芝治疗均可改善AIDS病人HAART后的免疫重建,换用克力芝治疗能较快提高病人CD4细胞水平。
[Abstract]:Objective to investigate the effect of highly effective antiretroviral therapy (HAART) on patients with HIV / AIDS (AIDS) with poor immune reconstitution, who were treated with lopinavir / ritonavir, or with traditional Chinese medicine (TCM). To compare the efficacy of these two methods in AIDS patients with poor immune reconstruction. Methods among 47 patients with immunoreconstructive disorder, 30 cases were treated with Clariz and 17 cases were treated with traditional Chinese medicine. The levels of CD4T lymphocytes (CD4 cells) in the two groups were observed six months after treatment. Results the level of CD4 cells in 30 patients in Klitazhi group was significantly higher than that in the former group half a year after the change of medicine, and that in 17 patients in the Chinese medicine group was significantly higher than that in the former group after the addition of traditional Chinese medicine for half a year. The comparison between the two groups was made between the two groups. Compared with the traditional Chinese medicine group, the level of CD4 cells in the Kleichiza group was significantly higher than that in the traditional Chinese medicine group (P 0.05). Conclusion both Chinese medicine and Clariz treatment can improve the immune reconstitution after HAART in AIDS patients, and the level of CD4 cells in AIDS patients can be improved quickly by the treatment of Clariz.
【作者单位】：昆明市第三人民医院;昆明市中医医院;
【分类号】：R512.91

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