重庆市男男性行为人群艾滋病患者抗病毒治疗效果分析

发布时间：2018-07-09 23:57

本文选题：获得性免疫缺陷性综合征 + 危性性行为　；参考：《重庆医学》2015年16期

【摘要】：目的了解重庆市男男性行为(MSM)人群艾滋病患者抗病毒治疗基本情况,评估不同基线CD4+T淋巴细胞数水平的抗病毒治疗效果。方法在国家艾滋病综合防治信息系统中收集资料,以患者开始治疗时基线CD4+T淋巴细胞数水平分类,采用回顾性队列研究方法观察和评估治疗效果,数据运用SPSS18.0软件进行统计分析。结果 1 758例治疗患者平均年龄(33.5±11.1)岁,CD4+T50个/μL、50~199个/μL、200~350个/μL、350个/μL者分别占7.7%、27.6%、54.9%、9.7%,治疗12个月后CD4+T值分别维持在150~250个/μL、250~350个/μL、350~450个/μL、450~550个/μL,治疗6个月后病毒载量抑制比例分别为70.2%、81.7%、84.2%、83.3%,治疗36个月生存率分别为0.81、0.93、0.98、1.00。结论 MSM人群艾滋病抗病毒治疗取得显著效果,早期治疗更有利于该人群免疫功能恢复,降低艾滋病病死率,控制疫情。
[Abstract]:Objective to investigate the basic status of antiviral therapy in MSM patients in Chongqing and to evaluate the effect of antiviral therapy on CD4 T lymphocyte counts in different baselines. Methods the data were collected in the National AIDS Integrated Prevention and treatment Information system, and the treatment effect was observed and evaluated by retrospective cohort study, according to the baseline CD4 T lymphocyte count level of the patients at the beginning of treatment. The data were analyzed by SPSS 18.0 software. Results the mean age of 1 758 patients was (33.5 卤11.1) years old: CD44T 50 / 渭 L 50 ~ 199 / 渭 L 200 ~ 350 / 渭 L, 350 / 渭 L 7.77.67.6x 54.9 / 渭 L, respectively. After 12 months of treatment, the CD44T values were maintained at 150 ~ 250 / 渭 L 250 ~ 350 / 渭 L ~ 450 ~ 450 / 渭 L ~ 450 ~ 550 / 渭 L / 渭 L, respectively. The 36-month survival rate was 0.81 0.93 卤0.981.00 respectively. Conclusion the effect of antiviral therapy on AIDS in MSM population is remarkable, and early treatment is more beneficial to the recovery of immune function, the reduction of AIDS mortality and the control of epidemic situation.
【作者单位】：重庆市疾病预防控制中心性病艾滋病预防控制所;
【基金】：重庆市卫生局2013年医学科研计划项目(2013-2-148)
【分类号】：R512.91

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